lysophosphatidylcholine


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ly·so·phos·pha·ti·dyl·cho·line

(lī'sō-fos'fă-tī'dil-kō'lēn),
A phosphatidylcholine in which a fatty acyl moiety has been removed from the C2 position of the glycerol group.
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Streamlined determination of lysophosphatidylcholines in dried blood spots for newborn screening of X-linked adrenoleukodystrophy.
Lysophosphatidylcholine reversibly arrests exocytosis and viral fusion at a stage between triggering and membrane merger.
2] is highly upregulated in atherosclerotic plaque; and through hydrolysis of oxidized LDL, this enzyme generates two pro-inflammatory mediators, lysophosphatidylcholine and non-esterified oxidized fatty acid.
Lysophosphatidylcholine and secretory phospholipase A2 in vascular disease: mediators of endothelial dysfunction and atherosclerosis.
Lysophosphatidylcholine enhances cytokine-induced interferon gamma expression in human T lymphocytes.
Local production of lipoprotein-associated phospholipase A2 and lysophosphatidylcholine in the coronary circulation: association with early coronary atherosclerosis and endothelial dysfunction in humans.
Preliminary studies conducted at Johns Hopkins University and the Kennedy Krieger Institute, both in Baltimore, suggest that combined LCMSMS (liquid chromatography coupled to tandem mass spectrometry) analysis of VLCFA in lysophosphatidylcholine may be useful as a newborn screening method for X-linked ALD and other peroxisomal disorders.
Lysophosphatidylcholine (LPC) induces proinflammatory cytokines by a platelet-activating factor (PAF) receptor-dependent mechanism.
Involve-ment of reactive oxygen species in human sperm acrosome reaction induced by A23187, lysophosphatidylcholine, and biological fluid ultrafiltrates.
The products of phospholipase A2 include lysophospholipids; we observed a significant increase of two forms of lysophosphatidylcholine, which was related to cold tolerance in that the least cold tolerant cultivar accumulated significantly less lysophosphatidylcholine than any of the other cultivars tested.

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