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lyophilization

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lyophilization /ly·oph·i·li·za·tion/ (li-of″ĭ-lĭ-za´shun) the creation of a stable preparation of a biological substance by rapid freezing and dehydration of the frozen product under high vacuum.
ly·oph·i·li·za·tion (l-f-l-zshn)
n.
The process of isolating a solid substance from solution by freezing the solution and vaporizing the ice away under vacuum conditions. Also called freeze-drying.

ly·ophi·lize (-lz) v.

lyophilization [li-of″ĭ-lĭ-za´shun]
the creation of a stable preparation of a biologic substance by rapid freezing and dehydration of the frozen product under high vacuum. See also freeze-drying.

lyophilization
the creation of a stable preparation of a biological substance by rapid freezing and dehydration of the frozen product under high vacuum. Called also freeze-drying.

lyophilization
Freeze drying A method for preserving foods or biologicals, where a substance–eg, coagulation factor VIII, is 'snap-frozen' in liquid nitrogen–-70ºC and placed in a high vacuum to remove the water vapor as it sublimes; once the water is removed, the substance is brought to room temperature and stored. Cf Quick-freeze technique.


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The non-profit centre, also known as Regen Med, is finalizing a new business plan and contract that will bring the lyophilization method and some advanced tissue cutting techniques to Thunder Bay.
Recipharm AB, one of the leading contract pharmaceutical development and manufacturing organizations, has purchased the lyophilization facilities of Inotech Labor AG in Basel, Switzerland.
Lyophilization is used for a limited number of applications, such as those that involve proteins, enzymes, microorganisms and blood plasma, all of which are heat sensitive.
 
 
 
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