lyophilization


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lyophilization

 [li-of″ĭ-lĭ-za´shun]
the creation of a stable preparation of a biologic substance by rapid freezing and dehydration of the frozen product under high vacuum. See also freeze-drying.

ly·oph·i·li·za·tion

(lī-of'i-li-zā'shŭn),
1. The process of isolating a solid substance from solution by freezing the solution and evaporating the ice under vacuum.
2. The process of imparting lyophilic properties to a substance.
Synonym(s): freeze-drying

lyophilization

/ly·oph·i·li·za·tion/ (li-of″ĭ-lĭ-za´shun) the creation of a stable preparation of a biological substance by rapid freezing and dehydration of the frozen product under high vacuum.

lyophilization

Freeze drying A method for preserving foods or biologicals, where a substance–eg, coagulation factor VIII, is 'snap-frozen' in liquid nitrogen–-70ºC and placed in a high vacuum to remove the water vapor as it sublimes; once the water is removed, the substance is brought to room temperature and stored. Cf Quick-freeze technique.

ly·oph·i·li·za·tion

(lī-of'i-lī-zā'shŭn)
The process of isolating a solid substance from solution by freezing the solution and evaporating the ice under vacuum.
Synonym(s): freeze-drying.

lyophilization

see FREEZE-DRYING.

lyophilization

the creation of a stable preparation of a biological substance by rapid freezing and dehydration of the frozen product under high vacuum. Called also freeze-drying.
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References in periodicals archive ?
Cryopreservation in liquid nitrogen and lyophilization are recommended and used by the American Type Culture Collection [12].
This report studies the global lyophilization equipment market during the forecast period of 2015 to 2020.
processing facilities have offered to train Regen Med staff in the lyophilization method, to assist them in equipment purchases, develop protocols and get accreditation with the American Association of Tissue Banks.
To overcome this issue, Actelion Pharmaceuticals adopted the fast lyophilization (LyoSpeed) methodology developed by Genevac, and implemented this using the Genevac HT-12 centrifugal evaporation systems.
Procedures such as lyophilization, freezing, and osmotic manipulation are necessary to render control materials stable.
The funds will be used to continue Elusys' lyophilization development program and validation of the commercial production process.
The market report defines and segments the Lyophilization Equipment Market on the basis of equipment type, scale of operations, application, accessories, and region, with analyses and projections of the market size of each of these segments, (USD Million).
Our Orbos lyophilization technology, through the freeze drying of reagents in small quantities, enables efficient manufacturing of reagents in a convenient and stable format.
Linde's proprietary VERISEQ[R] Nucleation controls formation of ice crystals using a sterile cryogenic ice fog resulting in enhanced lyophilization (freeze drying) cycles and improved product quality.
When coupled with the latest thermal stages, pharmaceutical scientists are able to determine particle size, locate contaminants and determine lyophilization parameters quickly and accurately.
Analyzes lyophilization technologies and market development issues