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lyophilization

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia, Hutchinson 0.04 sec.
lyophilization /ly·oph·i·li·za·tion/ (li-of″ĭ-lĭ-za´shun) the creation of a stable preparation of a biological substance by rapid freezing and dehydration of the frozen product under high vacuum.
ly·oph·i·li·za·tion (l-f-l-zshn)
n.
The process of isolating a solid substance from solution by freezing the solution and vaporizing the ice away under vacuum conditions. Also called freeze-drying.

ly·ophi·lize (-lz) v.

lyophilization
the creation of a stable preparation of a biological substance by rapid freezing and dehydration of the frozen product under high vacuum. Called also freeze-drying.

lyophilization
Freeze drying A method for preserving foods or biologicals, where a substance–eg, coagulation factor VIII, is 'snap-frozen' in liquid nitrogen–-70ºC and placed in a high vacuum to remove the water vapor as it sublimes; once the water is removed, the substance is brought to room temperature and stored. Cf Quick-freeze technique.


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Measurement of dialkyl phosphate metabolites of organophosphorus pesticides in human urine using lyophilization with gas chromatography-tandem mass spectrometry and isotope dilution quantification.
Przybyl, President and Chief Executive Officer stated, "Our third quarter results continue to reflect our commitment to achieve our 2006 stated objectives: 50% year-over-year revenue increase, 40% gross margin, positive net income, 20 ANDA regulatory filings, 10 product approvals, and the completion of our lyophilization validation efforts.
 
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