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lymphoepithelioma |
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lymphoepithelioma /lym·pho·epi·the·li·o·ma/ (lim″fo-ep″ĭ-thēl″e-o´mah) a pleomorphic, poorly differentiated carcinoma arising from modified epithelium overlying lymphoid tissue of the nasopharynx.
lymphoepithelioma [lim′fō·ep′ithē′lē·ō′mə] Etymology: L, lympha + Gk, epi, above, thele, nipple, oma, tumor a poorly differentiated neoplasm developing from the epithelium overlying lymphoid tissue in the nasopharynx. It occurs most frequently in young people of Asian origin. Also called lymphoepithelial carcinoma. lymphoepithelioma (lim´fōep´i-thē´lēō´m n a malignant neoplasm arising from the epithelium and lymphoid tissue of the nasopharynx and characterized by cells of both tissues; may occur in the palate. lymphoepithelioma Undifferentiated nasopharyngeal carcinoma A CA with a marked lymphocytic component Types–Schmincke type Diffuse mixing of epithelial and lymphoid elements, making the lesion difficult to distinguish from lymphoma,
since the epithelial cells may mimic lymphoblasts or the lacunar cell variants of Reed-Sternberg cells Regaud type Cohesive carcinoma cell aggregates that are large enough to make the epithelial nature of the tumor obvious
Diagnosis Immunoperoxidase stains for cytokeratin How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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This undifferentiated carcinoma is made up of cells of varying morphology, and it frequently contains clumps of benign T cells intermixed within the tumor mass; as a result, it is also called a lymphoepithelioma. The histologic features of the right nasopharyngeal specimen were consistent with a typical nasopharyngeal carcinoma of the lymphoepithelioma subtype. 3) Morphologically, MLEL resembles lymphoepithelioma (undifferentiated nasopharyngeal carcinoma with lymphoid stroma), and it is often difficult to distinguish MLEL from metastatic nasopharyngeal carcinoma of the salivary gland. |
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