lymphocyte activation

activation /ac·ti·va·tion/ (ak″tĭ-va´shun)

1. the act or process of rendering active.

2. the transformation of a proenzyme into an active enzyme by the action of a kinase or another enzyme.

3. the process by which the central nervous system is stimulated into activity through the mediation of the reticular activating system.

4. the deliberate induction of a pattern of electrical activity in the brain.

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allosteric activation  increase in enzyme activity by binding of an effector at an allosteric site that affects binding or turnover at the catalytic site.

contact activation  initiation of the intrinsic pathway of coagulation through interaction of coagulation factor XII with various electronegative surfaces.

lymphocyte activation  stimulation of lymphocytes by antigen or mitogens resulting in macromolecular synthesis (RNA, protein, and DNA) and production of lymphokines, followed by proliferation and differentiation of the progeny into various effector and memory cells.

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lymphocyte activation,

the stimulation of lymphocytes by antigens or mitogens, rendering them metabolically active and causing them to differentiate into effector cells.