12,13,15,16) More recently, some studies have demonstrated a potent anticancer activity of Lycorine, Pancratistatin and Urngimionorine alkaloids.
maritimum contains up to 16 alkaloids, including lycorine, maritidine, lycoramine, galanthamine narciclasine, lycoricidine, and pancratistatin.
The leaves of this plant contain a special chemical named lycorine
which have a suppressive effect on the roots, shoots of the rice weeds.
Cytotoxicity studies of lycorine
alkaloids of the Amaryllidaceae.
By doing a chemical screen in large numbers of zebrafish embryos, the researchers found that the compound lycorine
promotes interaction between the blood stem cell and its niche, leading to greater numbers of blood stem cells in the adult fish.
and the possible involvement of lycorine
One set of mutants was further subjected to growth in media containing 500 [mu]g/mL lycorine
to select for mutants that are also rho[sup.
Therefore, the large numbers of structurally diverse Amaryllidaceae alkaloids were chemically classified into several types based on their chemical skeleton such as the lycorine, crinine, homolycorine, galanthamine, montanine, pancratistatin, buflavine and cherylline-type (Unver 2007).
Antiinflammatory effects of lycorine and haemanthidine.
reduces mortality of human enterovirus 71-infected mice by inhibiting virus replication.
2] fraction, three alkaloids were isolated: lycorine
, vittatine and montanine.
, ambelline and two other unidentified alkaloids have been reported present (Powell and Taylor, 1967).