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lyase

   Also found in: Dictionary/thesaurus, Wikipedia 0.06 sec.
lyase /ly·ase/ (li´ās) any of a class of enzymes that remove groups from their substrates (other than by hydrolysis or oxidation), leaving double bonds, or that conversely add groups to double bonds.
ly·ase (ls)
n.
Any of a group of enzymes that catalyze the formation of double bonds by removing chemical groups from a substrate without hydrolysis or catalyze the addition of chemical groups to double bonds.

lyase
any of a class of enzymes that remove groups from their substrates (other than by hydrolysis), leaving double bonds, or that conversely add groups to double bonds.


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The research program includes the pleuromutilins, a novel class of antibiotics, and two target-based projects, isocitrate lyase (Icl) and InhA.
Boyd and Chakrabarty (70) studied alginate lyase production in P aeruginosa to determine whether increased expression of this enzyme affected the size of the alginate molecules (and therefore adhesion of the organisms).
The second enzyme of this pathway for which the structure has been solved to high resolution is chorismate lyase from Eschierichia coli.
 
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