lupus psychosis

lupus psychosis

Neurology A condition seen in 12% to 52% of Pts with SLE, broadly defined to include delusional and severe affective disease Clinical Frank psychosis, atypical psychosis, schizophreniform disorder, and severe affective disorders–eg, major depression and anxiety or panic disorders; some authors argue that major depression, anxiety, or panic may be caused by corticosteroids or may simply represent an appropriate reaction to the illness rather than genuine LP; LP, if it exists, is attributed to an antibody to P protein, a polypeptide in ribosomal phosphoproteins. See Systemic lupus erythematosus.
References in periodicals archive ?
15) In an open study of 13 patients with lupus psychosis, Mok and colleagues (34) reported a favorable response to a combination of high dose oral corticosteroids and oral cyclophosphamide for 6 months, followed by azathioprine as maintenance immunosuppressive therapy.
Association between lupus psychosis and anti-ribosomal P protein antibodies.
Treatment of lupus psychosis with oral cyclophosphamide followed by azathioprine maintenance: an open-label study.