lung surfactant


Also found in: Dictionary, Thesaurus, Encyclopedia.
Related to lung surfactant: Pulmonary surfactant, lung surfactant drugs

lung surfactant

a detergent-like agent that reduces the surface tension of the liquid film covering the inner lining of the pulmonary alveoli. As an alveolus becomes smaller during expiration, the surfactant becomes more concentrated, further reducing the surface tension and preventing alveolar collapse.

surfactant

(sur-fak'tant) [ surf(ace)-act(ive) a(ge)nt]
A surface-active agent that lowers surface tension (e.g., oils and various forms of detergents). Artificial surfactants may be given endotracheally to relieve respiratory distress.

lung surfactant

Pulmonary surfactant.

modified natural surfactant

A replacement phospholipid from a natural source with some components removed.

pulmonary surfactant

A lipoprotein secreted by type II alveolar cells that decreases the surface tension of the fluid lining the alveoli, permitting expansion. Synthetic lung surfactant is available for treating patients with respiratory distress syndrome. In obstetrics, fetal production of surfactant can be stimulated by administration of a glucocorticoid 24 to 48 hr before an inevitable preterm birth.
Synonym: lung surfactant See: betamethasone; lecithin-sphingomyelin ratio
References in periodicals archive ?
Comparison of Infasurf (calf lung surfactant extract) to Survanta (beractant) in the treatment and prevention of RDS.
Alveolar type II cells cNOS activity and ATP levels are increased by lung surfactant or DPPC vesicles.
This supportive study was designed as a non-inferiority trial comparing the Company's humanized lung surfactant, Surfaxin, to Curosurf(R), an approved pig-lung extract.
Surfaxin(R) is a novel, peptide-containing lung surfactant invented at The Scripps Research Institute.
Surfaxin(TM) is a novel, peptide-containing lung surfactant invented at The Scripps Research Institute.
Surfaxin(TM) (formerly known as KL4-Surfactant) is a novel, proprietary, peptide-containing lung surfactant invented at The Scripps Research Institute in La Jolla, California.
Surfaxin is a novel, proprietary, peptide-containing lung surfactant invented at The Scripps Research Institute and initially developed by Johnson & Johnson.
Surfaxin(TM) is a novel, proprietary, peptide-containing lung surfactant invented at The Scripps Research Institute.
Surfaxin(TM) (Formerly known as KL4-Surfactant) is a Novel, Proprietary, peptide-containing lung surfactant discovered at The Scripps Research Institute in La Jolla, Calif.
of Queensland) take a well-rounded approach, carefully considering the mathematics of interface behavior along with the physical properties in describing key concepts such as surface tension, wetting, absorption, emulsions and membranes, capillarity and the mechanics of surfaces, absorption and the thermodynamics of surfaces, absorption of at the gas-liquid interface, insoluble monolayers and Langmuir-Blodgett films, the liquid-liquid surface in membranes, the surfaces of solids, absorption at the gas-solid interface, the liquid-solid interface in colloids and biological interfaces such as membrane materials, bilayers, vesicles and liposomes, cell membranes and lung surfactants.
Complex Membranous Systems, exploring bacterial and neural membranes, lung surfactants, and other colloidal systems