lower esophageal sphincter


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Related to lower esophageal sphincter: pyloric sphincter

low·er e·soph·a·ge·al sphinc·ter (LES),

musculature of the gastroesophageal junction that is tonically active except during swallowing.

lower esophageal sphincter

n.
A ring of smooth muscle fibers at the junction of the esophagus and stomach. Also called cardiac sphincter, gastroesophageal sphincter.

lower esophageal sphincter

the terminal few centimeters of the esophagus, near the esophagogastric junction, which normally remain constricted except during swallowing and prevent reflux of gastric contents into the esophagus.

lower esophageal sphincter

A 3-5 cm in length zone of ↑ pressure at the junction of the distal esophagus with the gastric cardia, located at the hiatus, which forms a physical barrier in preventing gastric reflux; substances that ↑ the LES tone include gastrin, acetylcholine, serotonin, PGF2 a, motilin, substance P, histamine, pancreatic polypeptide

low·er e·soph·a·ge·al sphinc·ter

(LES) (lō'ěr es-ō-fa'jē-ăl sfingk'tĕr)
Musculature of the gastroesophageal junction that is tonically active except during swallowing.
References in periodicals archive ?
Kawahara H, Imura K, Nakajima K, et al: Motor function of the esophagus and the lower esophageal sphincter in children who undergo laparoscopic Nissen fundoplication.
Increased frequency of transient lower esophageal sphincter relaxation induced by gastric distention in reflux patients with hiatal hernia.
Q: Doctor, won't opiates decrease the lower esophageal sphincter tone?
Vasoactive intestinal peptide and platelet-activating factor, 2 eosinophil secretory products, have been shown to cause lower esophageal sphincter relaxation.
These foods relax the lower esophageal sphincter muscle, allowing stomach contents to wash back up, or their acidity can irritate the lining of the esophagus.
5) In our elderly patient, additional factors besides GERD--such as the use of medications that may decrease lower esophageal sphincter pressure, disturbance in esophageal motility from aging, and absence of the typical symptoms of heartburn that delayed adequate diagnosis--likely contributed to esophageal stenosis.
The lower esophageal sphincter (LES) is a relatively high pressure zone which separates the stomach from the esophagus.
Reflux is not caused by obstructive sleep apnea, but reflux may be facilitated by obstructive sleep apnea," she said, and called for more studies examining transient lower esophageal sphincter relaxations in obstructive sleep apnea patients.
To prevent mechanical dysfunction of the lower esophageal sphincter, you should avoid activities that increase the amount of pressure on your abdomen or increase the pressure on the lower esophageal sphincter.
It decreases the tonus of the lower esophageal sphincter in normal subjects and patients with achalasia.
1) Manometry is also the most accurate method of identifying the lower esophageal sphincter for pH catheter placement, ensuring valid 24-hour monitoring data.

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