lower esophageal sphincter


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Related to lower esophageal sphincter: pyloric sphincter

low·er e·soph·a·ge·al sphinc·ter (LES),

musculature of the gastroesophageal junction that is tonically active except during swallowing.

lower esophageal sphincter

n.
A ring of smooth muscle fibers at the junction of the esophagus and stomach. Also called cardiac sphincter, gastroesophageal sphincter.

lower esophageal sphincter

the terminal few centimeters of the esophagus, near the esophagogastric junction, which normally remain constricted except during swallowing and prevent reflux of gastric contents into the esophagus.

lower esophageal sphincter

A 3-5 cm in length zone of ↑ pressure at the junction of the distal esophagus with the gastric cardia, located at the hiatus, which forms a physical barrier in preventing gastric reflux; substances that ↑ the LES tone include gastrin, acetylcholine, serotonin, PGF2 a, motilin, substance P, histamine, pancreatic polypeptide

low·er e·soph·a·ge·al sphinc·ter

(LES) (lō'ěr es-ō-fa'jē-ăl sfingk'tĕr)
Musculature of the gastroesophageal junction that is tonically active except during swallowing.
References in periodicals archive ?
Lower Esophageal Sphincter - Muscle that opens to let food pass into the stomach and closes to stop stomach juices from backing up into the esophagus.
Manometric changes of the lower esophageal sphincter after sleeve gastrectomy in obese patients.
Hydrogen peroxide reduces lower esophageal sphincter tone in human esophagitis.
Pneumatic dilatation in patients with symptomatic diffuse esophageal spasm and lower esophageal sphincter dysfunction.
Smoking also has detrimental effects on the lower esophageal sphincter functioning effectively, so quitting cigarettes is vital.
This may be because, following the radiofrequency ablation to the deep submucosal space at the lower esophageal sphincter, collagen deposition needed time to mature.
Unfortunately, medications don't work for everyone, and a few patients may require a surgical procedure known as Nissen fundoplication, in which a surgeon wraps the upper part of the stomach (fundus) around the lower esophageal sphincter to strengthen it.
Sildenafil significantly decreases the tonus of the lower esophageal sphincter in normal individuals, patients with esophageal motor disorders, and with nutcracker esophagus.
The effects of peppermint oil are thought to derive from its ability to relax the lower esophageal sphincter, to block calcium channels, and to reduce colonic spasms.
Gastro-esophageal Reflux Disease is a chronic, often progressive disease resulting from a weak lower esophageal sphincter that allows harmful gastric fluid to reflux into the esophagus, resulting in both pain and injury to the esophageal lining.
GERD is a condition in which the lower esophageal sphincter, a muscular valve that separates the esophagus from the stomach, becomes too relaxed or weak and allows stomach acid to flow up into the esophagus, often causing considerable heartburn and other problems.
Unlike medical therapy, surgery was associated with normalization of lower esophageal sphincter pressure.

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