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louping ill

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louping ill
an acute encephalomyelitis affecting mostly sheep and red grouse (Lagopus scoticus), but occasionally other domestic animals and humans, caused by a flavivirus and transmitted by Ixodes ricinus. Clinically it is notable as a syndrome of fever, a peculiar bounding (louping) gait, paralysis and convulsions. Viruses that are closely related to louping-ill virus, and that cause very similar disease but in different regions of the world, include Russian spring-summer encephalitis virus, Turkish sheep encephalitis virus, Spanish sheep encephalitis virus and Greek goat encephalomyelitis. Called also ovine encephalomyelitis.


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A related flavivirus has been isolated in Norway from sheep; it was subsequently analyzed as louping ill virus (LIV), not TBEV (3).
The only zoonotic arboviruses isolated from field material in the United Kingdom are the flavivirus Louping ill virus (LIV) (4) and the bunyavirus Uukuniemi virus (5).
Disseminated staphylococcal infections that occur with tickborne fever kill [approximately equal to] 2% of field-raised sheep in the United Kingdom (20); louping ill, a tickborne viral encephalitis of goats is self-limited unless it occurs in conjunction with tickborne fever, when it is often fatal (20); bacterial and fungal secondary infections are more frequent in A.
 
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