losartan-hydrochlorothiazide

losartan-hydrochlorothiazide

Hyzaar® An antihypertensive with an angiotensin II receptor antagonist and a diuretic
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Those on the losartan-hydrochlorothiazide combination had an initial mean systolic reduction of 6 mm Hg, which increased to 14 mm Hg at week 8 and 16 mm Hg by the close of the treatment period.
Adverse events were somewhat more frequent in the elderly compared to non-elderly patients and somewhat more frequent in blacks compared to non-blacks for both the losartan-hydrochlorothiazide and the control groups.
Adverse events were somewhat more frequent in the elderly compared to non-elderly patients for both the losartan-hydrochlorothiazide and the control groups (see CLINICAL PHARMACOLOGY, Special Populations).
In these double-blind controlled clinical trials, the following adverse experiences reported with losartan-hydrochlorothiazide occurred in (greater than =)1 percent of patients, and more often on drug than placebo, regardless of drug relationship: