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loracarbef |
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loracarbef /lor·a·car·bef/ (lor″ah-kahr´bef) a carbacephem antibiotic closely related to cefaclor and having similar antibacterial actions and uses. loracarbef (lor´ n brand name: Lorabid; drug class: antibiotic, 2nd-generation cephalosporin; action: inhibits bacterial cell wall synthesis, which renders cell wall osmotically unstable; uses: gram-negative H. influenzae, E. coli, P. mirabilis, Klebsiella; gram-positive S. pneumoniae, S. pyogenes, S. aureus. loracarbef Lorabid® Therapeutics A synthetic β-lactam antibiotic of the carbecepham family, most effective against gram-positive cocci–eg, S pneumoniae, H influenzae, Branhamella catarrhalis, and
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Antibiotic susceptibility of upper respiratory tract pathogens in Sweden: a seven year follow-up study including loracarbef. Assessment of the susceptibility of Streptococcus pneumoniae to cefaclor and loracarbef in 13 countries. Among the cephalosporins tested, the rank order of activity based on a comparison of MICs was ceftriaxone [is greater than] cefpodoxime = cefuroxime [is greater than] cefprozil [is greater than] cefixime [is greater than] cefaclor = loracarbef [is greater than] ceftibuten. |
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