lopinavir


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lopinavir

 [lo-pin´ah-vir]
an HIV protease inhibitor, an antiviral agent used in combination with ritonavir in the treatment of human immunodeficiency virus infection; administered orally.

lopinavir

/lo·pin·a·vir/ (lo-pin´ah-vir) an antiviral HIV protease inhibitor, used with ritonavir in the treatment of HIV infection.

lopinavir

[lopin′ävir]
an HIV protease inhibitor, an orally administered antiviral agent used in combination with ritonavir in the treatment of human immunodeficiency virus infection.

lopinavir

An antiretroviral protease inhibitor with potent anti-HIV effect in clinical studies.
 
Adverse effects
Headache, diarrhea.
References in periodicals archive ?
When the researchers looked at the drug levels in the blood drawn from the mothers and infants at 12 weeks, they found the expected levels of lopinavir and ritonavir in the mothers, but none of either in the blood of the infants.
Since publishing our earlier work, we have now found that lopinavir selectively kills HPV-infected, non-cancerous cells, while leaving healthy cells relatively unaffected," said Dr Ian Hampson, from Manchester's School of Cancer and Enabling Sciences.
The virological efficacy results of boosted lopinavir seen here were consistent with previously reported efficacy results in treatment-experienced patients [6,7].
Kaletra was developed using the proprietary Meltrex(TM) melt-extrusion technology, a formulation process resulting in a stable, solid dispersion of Kaletra, translating to fewer pills while maintaining the same amount of lopinavir and ritonavir.
The lower-strength tablet contains 100 mg of lopinavir and 25 mg of ritonavir compared with the current tablet strength of 200 mg of lopinavir and 50 mg of ritonavir.
Lopinavir / Ritonavir, oral solution, 80 mg / 20 mg - 1 ml
Another 48-week sub-analysis of isolates from patients in the RESIST studies found that a numerically higher percentage of patients who were genotypically lopinavir-sensitive, but had three or more lopinavir score mutations, taking a tipranavir/r-containing regimen achieved undetectable viral loads (less than 50 copies/mL) compared to patients who stayed on a lopinavir/r-containing regimen.
Patients Treated With Boosted Invirase 500 Were Significantly Less Likely to Develop Elevated Lipids Than Boosted Lopinavir
The study was designed to assess the pharmacokinetic (PK) interaction, or effect on overall exposure in the body, of the combination lopinavir/ritonavir on the PK of LIVALO, and secondarily any potential PK effect of LIVALO on lopinavir and ritonavir.
Supply of drugs Lopinavir / Ritonavir bound for Corporate Public Health Agency Hospital de Poniente.
The new formulation of Kaletra will provide patients with a tablet composed of 200 mg lopinavir and 50 mg ritonavir, as compared to the current soft capsule, which contains 133.
Lopinavir/ritonavir should not be taken by patients who have had an allergic reaction to any of its ingredients, including lopinavir or ritonavir.