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loop diuretic

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loop diuretic
n.
A class of diuretic agents that act by inhibiting reabsorption of sodium and chloride.

loop diuretic.
See diuretic.

diuretic (dī´yret´ik),
n 1. a drug that increases the formation of urine.
adj 2. pertaining to the increased formation of urine. Used mainly in the initial treatment of hypertension (high blood pressure).
diuretic, loop,
n a high-potency therapeutic agent used to control hypertension by exerting influence on the loop of Henle in order to facilitate the removal of surplus water and sodium from the body. See furosemide.

loop diuretic
Nephrology Any of a family of potent–'high-ceiling'–diuretics that act on Henle's loop, evoking excretion of 20-25% of filtered Na+ Indications Pulmonary edema, CHF, renal failure Examples Furosemide, ethacrinic acid, bumetanide, demadex


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But the ototoxicity level often goes out of control when patients have already been prescribed an ototoxic medication such as Lasix or Bumex that are actually loop diuretics and even aminoglycosides.
The ototoxic effects of loop diuretics seem to be associated with the stria vascularis, which is affected by changes in the ionic gradients between the perilymph and endolymph.
The researchers, who looked at Part D plans in California, studied eight treatment classes, including angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, [beta]-blockers, calcium channel blockers, loop diuretics, selective serotonin reuptake inhibitors, statins, and thiazide diuretics.
 
 
 
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