lodoxamide

lodoxamide

 [lo-dok´sah-mīd]
a mast cell stabilizer that inhibits immediate hypersensitivity, applied topically to the eye as the tromethamine salt for treatment of allergen-induced conjunctivitis, keratitis, and keratoconjunctivitis.

lodoxamide

/lo·dox·a·mide/ (lo-dok´sah-mīd) a mast cell stabilizer and antiallergic; applied topically to the eye as the tromethamine salt for the treatment of allergen-induced conjunctivitis, keratitis, and keratoconjunctivitis.

lodoxamide

[lo-dok′sämīd]
a mast cell stabilizer that inhibits immediate hypersensitivity, applied topically to the eye as the tromethamine salt for treatment of allergen-induced conjunctivitis, keratitis, and keratoconjunctivitis.

lodoxamide

A mast cell-stabilizing drug that prevents the release of HISTAMINE in allergic conditions, formulated as eye drops for the treatment of allergic CONJUNCTIVITIS. A brand name is Aldomide.

mast cell stabilizers

Prophylactic drugs used to treat allergic conjunctivitis, vernal conjunctivitis, giant pupillary conjunctivitis, superior limbic keratoconjunctivitis. They act by stabilizing the membranes of mast cells thus preventing the release of histamine. Common agents are sodium cromoglicate (cromolyn sodium), lodoxamide, nedocromil sodium, olopatadine hydrochloride and pemirolast potassium. See antihistamine; hypersensitivity.
References in periodicals archive ?
6,43,44) However, the presence of limbal or corneal disease requires urgent referral--while patients await their appointment, pharmacyonly mast cell stabilisers may be advised such as sodium cromoglycate 2% and lodoxamide 0.
As with VKC, AKC requires long-term therapy with topical mast cell stabilisers such as sodium cromoglycate, lodoxamide and nedocromil to treat the allergic inflammation in mild cases.
Table 1 Topical ophthalmic medications available for the treatment of ocular allergy in the UK Medication Name Formulation Optometrist class availability Mast cell Sodium Sodium Entry level stabiliser Cromoglycate Cromoglycate 2% but in (non- maximum proprietary) pack size of 10mL Catacrom Sodium At least (Moorfields Cromoglycate 2% Additional Pharmceu- (single use) Supply level ticals) Rapitil Nedocromil At least (Sanofi- Sodium 2% Additional Aventis) Supply level Alomide Lodoxamide 0.
Lodoxamide tromethamine and cromolyne sodium should be preferred in severe cases (65).
13-16) The logic of such a treatment might be questioned since sodium cromoglicate is not considered to have any constitutive anti-inflammatory activity; the removal of the stimulus to inflammation should help and better results might be obtained with other mast cell stabilisers/anti-eosinophil drugs such as lodoxamide or nedocromil sodium (both available to AS optometrists).
Which of the following daily doses of lodoxamide eye drops would be commonly recommended to treat grade 2 CLPC?
For chronic and recurrent allergic conjunctivitis, part of an appropriate management approach is the use of 'mast cell stabilisers', (21) with several drugs marketed in the UK (eg, sodium cromoglicate, lodoxamide and nedocromil sodium).
All of these cromoglicate products can be accessed by optometrists, along with a P-medicine in the form of lodoxamide.
d) Discontinue lens wear and use lodoxamide eye drops QDS