local anaphylaxis

anaphylaxis /ana·phy·lax·is/ (-fĭ-lak´sis) anaphylactic shock; a manifestation of immediate hypersensitivity in which exposure of a sensitized individual to a specific antigen or hapten results in life-threatening respiratory distress, usually followed by vascular collapse and shock and accompanied by urticaria, pruritus, and angioedema.

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active anaphylaxis  that produced by injection of a foreign protein.

antiserum anaphylaxis  passive a.

local anaphylaxis  that confined to a limited area, e.g., cutaneous anaphylaxis.

passive anaphylaxis  that resulting in a normal person from injection of serum of a sensitized person.

passive cutaneous anaphylaxis  PCA; localized anaphylaxis passively transferred by intradermal injection of an antibody and, after a latent period (about 24 to 72 hours), intravenous injection of the homologous antigen and Evans blue dye; blueing of the skin at the site of the intradermal injection is evidence of the permeability reaction. Used in studies of antibodies causing immediate hypersensitivity reaction.

reverse anaphylaxis  that following injection of antigen, succeeded by injection of antiserum.

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local anaphylaxis

n.

The immediate, temporary, localized anaphylactic response of a sensitized individual following injection of an antigen into the skin.

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local anaphylaxis

Etymology: L, locus, place; Gk, ana + phylaxis

a hypersensitivity reaction in which injections of an antigen result in localized swelling and necrosis of the skin and subcutaneous tissues.