lobular carcinoma in situ


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Related to lobular carcinoma in situ: invasive lobular carcinoma

non·in·fil·trat·ing lob·u·lar car·ci·no·ma

carcinoma of the breast in which small tumor cells fill preexisting acini within lobules, without invading the surrounding stroma.

lobular carcinoma in situ

Atypical lobular hyperplasia, LCIS Oncology A precancerous epithelial lesion of the female breast;13 of those with LCIS develop invasive CA; 8% of LCIS do not form a discrete mass. Cf Ductal carcinoma in situ.
References in periodicals archive ?
Lobular carcinoma in situ is classified as classic or pleomorphic, based on nuclear cytologic features.
A, Florid variant of lobular carcinoma in situ is characterized by marked ductal (nonpagetoid) and lobular expansion by neoplastic cells, similar to that seen in solid-type ductal carcinoma in situ with low- to intermediate-grade nuclei.
A, Classic-type lobular carcinoma in situ (LCIS) with low nuclear grade type A cells.
Pleomorphic lobular carcinoma in situ was at the margin in 6 of 26 cases (23%), 1 mm from the margin in 7 of 26 cases (27%; Figure 3), 1.
Calcifications of lobular carcinoma in situ of the breast: radiologic-pathologic correlation.
Florid" lobular carcinoma in situ with necrosis and calcification: a clinicopathologic, immunohistochemical and molecular analysis [abstract].
Simultaneous loss of E-cadherin and catenins in invasive lobular breast cancer and lobular carcinoma in situ.
E-cadherin inactivation in lobular carcinoma in situ of the breast: an early event in tumorigenesis.
Lobular carcinoma in situ of the breast: detailed analysis of 99 patients with average follow-up of 24 years.
Pleomorphic lobular carcinoma in situ and high-grade DCIS are currently managed similarly, and hence distinguishing between these 2 entities is not of the clinical import discussed above.
Comparative genomic hybridization analysis of lobular carcinoma in situ and atypical lobular hyperplasia and potential roles for gains and losses of genetic material in breast neoplasia.
We have observed a similar staining pattern in rare cases of lobular carcinoma in situ of the breast.