liver function test

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liver function test (LFT)

one of several tests used to evaluate various functions of the liver, including metabolism, storage, filtration, and excretion. Kinds of liver function tests include alanine aminotransferase test, alkaline phosphatase test, prothrombin time, serum bilirubin.

liver function test



A blood test for a specific aspect of liver metabolism. Because of the diversity of liver functions and the disorders that may affect those functions, no single test provides a reliable measure of overall liver function. The ability to excrete bile pigments is measured by determining the serum bilirubin level; the levels of serum enzymes such as the aminotransferases aspartate and alanine may be used to assess damage to the liver cells and biliary tract obstruction or dysfunction. Levels of the serum proteins albumin and globulin and their ratio are used to judge the synthetic functions of the liver. Certain blood clotting factors are also synthesized in the liver, and abnormalities may indicate impairments in hepatic synthesis. Blood ammonia levels are elevated in some patients with either acute or chronic liver disease; marked elevations may suggest acute or chronic liver failure.
See: liver
References in periodicals archive ?
This indication is based on the ability of CHOLBAM to markedly improve or normalize liver function tests and to improve general health as measured by weight gain.
An independent professional review recommended that globulin (derived from total protein and albumin) should be included in all liver function test profiles.
Levels of other laboratory investigations, including urinalysis, blood sugar, liver function test, blood urea nitrogen, and creatinine, were normal.
On investigation blood sugar of the patient was very high and potassium level was low while liver function tests were also not normal.
Shiza is now undergoing liver function tests at SMC to detect inflammation and damage to the liver.
According to the study, 62 percent of the patients had improvements in clinical conditions associated with hepatic decompensation and/or improvement in liver function tests.
the administration of 1-methionine and the persistent improvement of liver function tests in a patient with hepatitis C
METHODS: Thirty patients were randomly divided into two groups, matched with respect to clinical features, impairment of hepatic function (as judged by liver function tests including antipyrine elimination) and immunosuppression (phagocytic and killing capacities of neutrophils).
If cirrhosis is suspected, liver function tests will be done as well as ultrasound scanning, MRI or CT scans.
Liver function tests measure the presence of enzymes in the blood that are produced by the liver.
Clinicians are being advised to conduct liver function tests before initiating treatment and during therapy.