live oral poliovirus vaccine


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po·li·o·vi·rus vac·cines

1. inactivated poliovirus vaccine (IPV), an aqueous suspension of inactivated strains of poliomyelitis virus (types 1, 2, and 3) used by injection; has largely been replaced by the oral vaccine;
2. oral poliovirus vaccine (OPV), an aqueous suspension of live, attenuated strains of poliomyelitis virus (types 1, 2, and 3) given orally for active immunization against poliomyelitis.

live oral poliovirus vaccine

a vaccine prepared from three strains (trivalent) of live polioviruses. Primary immunization with the vaccine usually begins at the age of 2 months.

live oral poliovirus vaccine

, poliovirus vaccine, live oral
A vaccine prepared from three types of live attenuated polioviruses. In 1999, an advisory panel to the CDC recommended that its routine use be discontinued. Because it contains a live, although weakened virus, it had been causing 8 to 10 cases of polio each year in the U.S. This risk was deemed no longer acceptable since by that date polio epidemics had been eliminated in the U.S. Therefore, since 1999 the live oral poliovirus vaccine has not been recommended or routinely given in the U.S. Instead only the inactivated poliovirus vaccine is approved and given in the U.S. Recommendations outside the U.S, , where polio outbreaks still occur, include the use of live oral polio vaccines. Synonym: Sabin vaccine
See also: vaccine