lithocholic acid


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lithocholic acid

 
a secondary bile acid formed by dehydroxylation of chenodeoxycholic acid in the intestine; some is reabsorbed and forms conjugates with glycine and taurine.

lith·o·cho·lic ac·id

(lith'ō-kō'lik as'id),
One of the acids isolated from human bile as well as from that of cows, rabbits, sheep, and goats.

lithocholic acid

the product of bacterial metabolism of bile acids in the intestine. Insoluble and not reabsorbed.
References in periodicals archive ?
Those bile acids go to the small intestine and are broken down into secondary bile acids, one of which is lithocholic acid.
Lithocholic acid can break apart DNA strands, form bonds with DNA that disrupt genes, and inhibit DNA repair.
Additionally, lithocholic acid and deoxycholic acid were noted as the major bile-acid components; both this and the 5[Beta]-stanol distribution, dominated by coprostanol, attested to a human source.
The non-steroidal ligands may be important tools for studying the pharmacology of the receptor, because they may not have the property of bile acids and are not metabolized to form harmful lithocholic acid (Fischer et al.