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lissencephaly |
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lissencephaly /lis·sen·ceph·a·ly/ (lis″en-sef´ah-le) agyria.lissencephal´ic lissencephaly. See agyria . lissencephaly a malformation in which the gyri of the cerebral cortex are not normally developed. In dogs it has been associated with behavioral abnormalities, visual deficits, ataxia and seizures. Called also agyria. lissencephaly Neurology A brain malformation that is isolated or associated with other syndromes–eg, Miller-Dieker syndrome, Norman-Roberts syndrome, characterized by absence–agyria or incomplete development–pachygyria of
cerebral gyri Clinical Microcephaly, seizures, profound mental retardation, feeding difficulties, growth retardation, impaired motor activity How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| 6%) pediatric patients with neuroinvasive WNV disease died: an infant with underlying lissencephaly and a 14-year-old boy with immune dysfunction. If a mutation in the gene blocks their formation, a newborn will suffer from a severe form of mental retardation caused by lissencephaly, or "smooth brain" disease. |
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