liposome


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

liposome

 [lip´o-sōm]
a microscopic spherical particle formed by a lipid bilayer enclosing an aqueous compartment.

lip·o·some

(lip'ō-sōm),
1. A spheric particle of lipid substance suspended in an aqueous medium within a tissue.
2. Any small, roughly spheric artificial vesicle consisting of a lipid bilayer enclosing some of the suspending medium.
[lipo- + G. sōma, body]

liposome

/lipo·some/ (lip´o-sōm) a microscopic spherical particle formed by a lipid bilayer enclosing an aqueous compartment.

liposome

(lĭp′ə-sōm′, lī′pə-)
n.
A microscopic artificial vesicle consisting of an aqueous core enclosed in phospholipid molecules, used to convey vaccines, drugs, or other substances to target tissues.

lip′o·so′mal adj.

liposome

[lip′əsōm]
Etymology: Gk, lipos, fat, soma, body
a small, spheric particle consisting of a bilayer of phospholipid molecules surrounding an aqueous solution.

liposome

Lipid vesicle Drug delivery A synthetic, uniform bilayer lipid membrane-bound vesicle formed by emulsification of cell membranes in dilute salt solutions, which is used to deliver toxic drugs–eg, amphotericin B, doxorubicin, pentavalent antimony–tagging them with an organ-specific antibody. See Liposome-encapsulated amphotericin B, Stealth liposome.

liposome

an artificially constructed PHOSPHOLIPID VESICLE, which can be used in various biological experiments. Certain drugs may be incorporated into liposomes in order to administer them. In this way the drugs may be protected from degradation and may not exert general toxicity when introduced into the bloodstream.

Liposome

Fat molecule made up of layers of lipids.
Mentioned in: Gene Therapy

liposome

a spherical structure, usually multilamelate, prepared from eukaryotic cell membranes which may be used as a carrier for glycoprotein antigens and drugs.
References in periodicals archive ?
The liposomes are used for taste masking which allows it to cover up the bitter taste of the amino acid while delivering a daily supply of the cats' essential nutrients.
The liposomes can be filled with different substances and used as vehicles for administration of drugs or nutrients.
But a new research from University of Southern Denmark has shown that liposomes are not capable of transporting themselves deep into the skin, and thus they are not capable of transporting active ingredients deep into the skin.
The researchers made the liposomes by adding a ginseng dispersion into soy lecithin powder under shear force conditions.
Efficient gene delivery with serum into human cancer cells using targeted anionic liposome.
He says, "Our liposome immunoassay detection limit without enrichment is about one thousand target organisms per milliliter or gram.
Because each liposome contains hundreds of thousands to perhaps millions of marker molecules, there is a large amplification effect when the liposome is ruptured and the markers are released," says Durst.
The new liposome tumor targeting technology being licensed will be developed as an extension of the Company's current delivery technology, with a goal toward more powerfully focusing delivery of the antisense and FAK siRNA cancer treatments to the tumor tissue.
Kohane and colleagues hope to conduct further tests to better understand how the liposomes are blocking infection.
Liposomes have already been approved to deliver drugs to cells in other diseases.
Orphan drug designation entitles Hana Biosciences to seven years of market exclusivity for Marqibo([R]) (vincristine sulfate liposomes injection) in the treatment of adult patients with ALL.
Recent reports from the International Workshop on Meibomian Gland Dysfunction* (MGD) demonstrate an improvement of symptoms associated with Evaporative Dry Eye and Stage 2 MGD when a liposome spray, namely Tears Again advanced Liposome Spray, was added to treatment plans.