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liposome

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liposome /lipo·some/ (lip´o-sōm) a microscopic spherical particle formed by a lipid bilayer enclosing an aqueous compartment.
lip·o·some (lp-sm, lp-)
n.
An artificial microscopic vesicle consisting of an aqueous core enclosed in one or more phospholipid layers, used to convey vaccines, drugs, enzymes, or other substances to target cells or organs.

Liposome
Fat molecule made up of layers of lipids.
Mentioned in: Gene Therapy

liposome
[lip′əsōm]
Etymology: Gk, lipos, fat, soma, body
a small, spheric particle consisting of a bilayer of phospholipid molecules surrounding an aqueous solution.

liposome [lip´o-sōm]
a microscopic spherical particle formed by a lipid bilayer enclosing an aqueous compartment.

liposome
a spherical structure, usually multilamelate, prepared from eukaryotic cell membranes which may be used as a carrier for glycoprotein antigens and drugs.

liposome
Lipid vesicle Drug delivery A synthetic, uniform bilayer lipid membrane-bound vesicle formed by emulsification of cell membranes in dilute salt solutions, which is used to deliver toxic drugs–eg, amphotericin B, doxorubicin, pentavalent antimony–tagging them with an organ-specific antibody. See Liposome-encapsulated amphotericin B, Stealth liposome.


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The catheter would use ultrasound to first image the tumour, and then direct a higher-power beam to generate heat at the site, melting the liposome shells and releasing the chemotherapy directly to the tumour.
We implemented this approach in practice using our liposome anti HIV/AIDS preparation FTL/AZT/PEBA containing lithium as a specific non-competitive blocker of the polyphosphoinositide pathway (8, 9) and 3'-azido-3'deoxythymidine (AZT, azidothymidine) as an antiretroviral agent, both of them obligatory encapsulated in liposomes.
The opening chapter describes liposome preparation methods, analytical techniques, the stability of liposome formulations, and drug-loaded liposomes for treating cancer, infections, arthritis, asthma, and psoriasis.
 
 
 
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