liposarcoma


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Related to liposarcoma: lipoma

liposarcoma

 [lip″o-sahr-ko´mah]
a malignant tumor characterized by large anaplastic lipoblasts, sometimes with foci of normal fat cells.

lip·o·sar·co·ma

(lip'ō-sar-kō'mă),
A malignant neoplasm of adults that occurs especially in the retroperitoneal tissues and the thigh, usually deep in the intermuscular or periarticular planes; histologically, liposarcoma is a large tumor that may be composed of well-differentiated fat cells or may be dedifferentiated, either myxoid, round-celled, or pleomorphic, usually in association with a rich network of capillaries; recurrences are common, and dedifferentiated liposarcoma metastasizes to the lungs or serosal surfaces.
[lipo- + sarx, flesh, + -oma, tumor]

liposarcoma

/lipo·sar·co·ma/ (lip″o-sahr-ko´mah) a malignant mesenchymal tumor usually occurring in the intermuscular fascia in the upper thigh, characterized by primitive lipoblastic cells with varying degrees of lipoblastic or lipomatous differentiation, sometimes with foci of normal fat cells.

liposarcoma

[lip′ōsärkō′mə] pl. liposarcomas, liposarcomata
Etymology: Gk, lipos + sarx, flesh, oma, tumor
a malignant growth of primitive fat cells that occurs in the deep soft tissue of the extremities and retroperitoneum. It is the most common soft tissue sarcoma. Also called lipoma sarcomatodes.

lip·o·sar·co·ma

(lip'ō-sahr-kō'mă)
A malignant neoplasm of adults that occurs especially in the retroperitoneal tissues and the thigh; planes composed of well-differentiated fat cells, or may be dedifferentiated, either myxoid, round celled, or pleomorphic; recurrences are common, and dedifferentiated liposarcomas metastasize to the lungs or serosal surfaces.
Synonym(s): lipoblastoma (1) .
[lipo- + sarx, flesh, + -oma, tumor]

liposarcoma

A very rare malignant tumour of fatty tissue. Liposarcomas usually occur in the fat on the inside of the back wall of the abdomen or in the MEDIASTINUM of elderly people.

liposarcoma (liˈ·pō·sar·kōˑ·m),

n a malignant tumor that comprises immature fat cells.
Enlarge picture
Liposarcoma.

liposarcoma

a malignant tumor characterized by large anaplastic lipoblasts, sometimes with foci of normal fat cells.
References in periodicals archive ?
The effectiveness and safety of Yondelis were demonstrated in 518 clinical trial participants with metastatic or recurrent leiomyosarcoma or liposarcoma.
MDM2 and CDK4 immunostainings are useful adjuncts in diagnosing well-differentiated and dedifferentiated liposarcoma subtypes: a comparative analysis of 559 soft tissue neoplasms with genetic data.
Extracellular and Connective Tissue Components Background stroma Neuropil Neuroblastoma Desmoplasia Desmoplastic small cell tumor Myxoid Liposarcoma, embryonal rhabdomyosarcoma Calcifications Neuroblastoma, synovial sarcoma, and MNST Lymphoglandular Non-Hodgkin lymphoma bodies Other elements Neuronal cells Neuroblastoma, ectomesenchymoma Rhabdomyoblasts Rhabdomyosarcoma Cross-striations Rhabdomyosarcoma Blastema/ Nephroblastoma, pleuropulmonary epithelium blastoma Abbreviation: MNST, malignant nerve sheath tumor.
But if the drug fails against liposarcoma, Sanofi will reluctantly admit defeat.
Although it is not always possible to definitively diagnose a hibernoma, based on imaging alone, this histologic lipomatous variant should be considered in the differential diagnosis when radiologists encounter a lesion that does not exhibit the typical features of either a simple lipoma or a liposarcoma.
Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor gamma and the retinoid X receptor.
He was diagnosed with Liposarcoma, a rare cancer with only 1,200 new cases diagnosed each year in the country, at the age of 30.
Lactoferrin has previously been described to inhibit the selective uptake of HDL cholesteryl esters by 35%-50% in human primary adipocytes and SW872 liposarcoma cells (22).
CASE FACTS: Betty Giovanello underwent abdominal surgery for recurrent retroperitoneal liposarcoma at Redding Medical Center on August 19, 1966.
In addition to breast cancer, PD-991 is currently being evaluated through Pfizer-sponsored and investigator-initiated research in other cancers, including liposarcoma, non-small cell lung cancer, liver cancer, ovarian cancer, glioblastoma, refractory solid tumors, multiple myeloma, and mantle cell lymphoma.
Food and Drug Administration (FDA) has approved YONDELISA (trabectedin) for the treatment of patients with unresectable (unable to be removed with surgery) or metastatic liposarcoma (LPS) or leiomyosarcoma (LMS) who received a prior anthracycline-containing regimen.
Food and Drug Administration (FDA) for the treatment of patients with unresectable or metastatic liposarcoma (LPS) or leiomyosarcoma (LMS) who have received a prior anthracycline-containing regimen.