lipoproteins


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lipoproteins

Any complex of fats with protein. A conjugated protein consisting of a simple protein combined with a fat (lipid) group. The blood lipoproteins, which are the cholesterol carriers of the body, are classified by density, in accordance with the proportions of protein, as very low density (VLDL), low density (LDL) and high density (HDL). LDLs contain relatively large amounts of cholesterol. HDLs contain 50% of protein and only 20% of cholesterol. LDLs transport lipids to muscles and to fat stores and are associated with the arterial disease ATHEROSCLEROSIS and thus heart disease and STROKE. HDLs are protective against these diseases because their main role is to transport cholesterol from the periphery back to the liver. They also carry paraoxanase enzymes that limit oxidative modification of LDLs necessary before cholesterol can be laid down in arterial walls. Blood concentration of HDL cholesterol shows a strong inverse correlation with the risk of coronary heart disease.

Lipoproteins

The packages in which cholesterol and triglycerides travel throughout the body.
Mentioned in: Lipoproteins Test

lipoproteins

(lip´ōprō´tēns),
n.pl biochemical compounds that contain both lipid and protein. Most lipids in plasma are present in the form of lipoproteins. There are two main types: low density and high density.
lipoproteins, high-density (HDLs),
n.pl the types containing approximately 50% protein that transport cholesterol to the liver for disposal. High HDL levels are associated with low body cholesterol and decreased risk of heart disease.
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Lipoma of the lip.
lipoproteins, low-density (LDLs),
n.pl the types containing approximately 21% protein that deliver cholesterol from the liver to cells throughout the body. High amounts of LDLs may raise cholesterol levels in the body and increase the risk of developing atherosclerosis.

Patient discussion about lipoproteins

Q. what are the sources for high density lipoprotein? I have heard that high density lipoprotein is good for heart. What differences does it make in heart’s health and what are the sources for high density lipoprotein?

A. Hi Liam, it is very important that we have high density lipoprotein (HDL) in our body. The fact is that the HDL is formed inside the body. They are known as good cholesterol as they are famous for their protection for heart against the heart diseases. It has been found that Vitamin B3 or Niacin consumption increases the count of HDL. It’s good to cut on the diet having more of saturated fats and oils, which increases the chances of heart attack.

More discussions about lipoproteins
References in periodicals archive ?
LDL are the major lipoproteins responsible for delivery of exogenous cholesterol to the tissues.
Low density lipoprotein (LDL) carries cholesterol from the liver to the cells and can cause a harmful build-up if there is too much for the cells to use.
have proposed age- and gender-specific thresholds that can be used to identify abnormal lipoprotein levels in adolescents that might put them at risk for cardiovascular disease later in life (Circulation 2006;114:1056-62).
Their analyses showed that volunteers' very low-density lipoproteins (VLDL) contained significantly more triglycerides following the refined-grain test breakfast than after the whole-grain test breakfast.
Low triglyceride levels affect calculation of low-density lipoprotein cholesterol values.
VAP has been essential to my research and clinical practice allowing rigorous measurement of all major lipoprotein cholesterol fractions and subfractions.
In diabetics, there is increased oxidation of lipoproteins [32, 33] including Lp(a) because it is as prone as LDL to oxidation [34, 35].
Tolfrey et al [9], in their research, believe that the fact that the natural levels of lipoproteins stay the same is due to the daily body activities in adults and children.
These remnants and other small lipoproteins (LDL and HDL) can undergo hydrolysis of TG by hepatic lipase, forming progressively smaller particles.
1,2) The risk is substantially elevated in patients with end-stage renal disease (ESRD) (such patients show various abnormalities in plasma-lipids and lipoproteins that are called uremic dyslipidemia.
The components of the typical lipoprotein panel are the lipids cholesterol and triglyceride, as well as 3 lipoproteins: high-density lipoprotein (HDL), low-density lipoprotein (LDL), and very low-density lipoprotein (VLDL).