lipoprotein

lipoprotein /lipo·pro·tein/ (-prō´tēn) a complex of lipids and apolipoproteins, the form in which lipids are transported in the blood.

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α-lipoprotein , alpha lipoprotein one with electrophoretic mobility equivalent to that of the α1-globulins, e.g., high-density lipoprotein.

β-lipoprotein , beta lipoprotein one with electrophoretic mobility equivalent to that of the β-globulins, e.g., low-density lipoprotein.

floating beta lipoproteins  β.

high-density lipoprotein  (HDL) a class of plasma lipoproteins that promote transport of cholesterol from extrahepatic tissue to the liver for excretion in the bile; serum levels have been negatively correlated with premature coronary heart disease.

intermediate-density lipoprotein  (IDL) a class of lipoproteins formed in the degradation of very-low-density lipoproteins; some are cleared rapidly into the liver and some are degraded to low-density lipoproteins.

low-density lipoprotein  (LDL) a class of plasma lipoproteins that transport cholesterol to extrahepatic tissues; high serum levels have been correlated with premature coronary heart disease.

Lp(a) lipoprotein  a lipoprotein particle containing apolipoprotein B-100 as well as an antigenically unique apolipoprotein; its occurrence at high levels in plasma has been correlated with increased risk of heart disease.

pre-β-lipoprotein , pre-beta lipoprotein very-low-density lipoprotein

sinking pre-β-lipoprotein  Lp(a) l.

very-high-density lipoprotein  (VHDL) a class of lipoproteins composed predominantly of proteins and also containing a high concentration of free fatty acids.

very-low-density lipoprotein  (VLDL) a class of lipoproteins that transport triglycerides from the intestine and liver to adipose and muscle tissues; they contain primarily triglycerides with some cholesteryl esters.

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lip·o·pro·tein (lp-prtn, lp-)

n.

Any of a group of conjugated proteins that have at least one lipid component and are the principal means by which lipids are transported in the blood.

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Lipoprotein

A complex molecule that consists of a protein membrane surrounding a core of lipids. Lipoproteins carry cholesterol and other lipids from the digestive tract to the liver and other body tissues. There are five major types of lipoproteins.

Mentioned in: Cholesterol Test, Hypolipoproteinemia

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lipoprotein

[lip′ōprō′tēn]

Etymology: Gk, lipos + proteios, first rank

a conjugated protein in which lipids form an integral part of the molecule. They are synthesized primarily in the liver; contain varying amounts of triglycerides, cholesterol, phospholipids, fat-soluble vitamins, and protein; and are classified according to their composition and density. Practically all of the plasma lipids are present as lipoprotein complexes. The elevation of low-density lipoproteins (LDLs) in plasma is associated with an increased risk of atherosclerosis. Normal adult levels of lipoproteins include high-density lipoproteins, greater than 35 mg/dl; LDLs, 60 to 180 mg/dl; and very low-density lipoproteins, 25% to 50%. Kinds of lipoproteins are chylomicrons, high-density lipoproteins, low-density lipoproteins, and very low-density lipoproteins.

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lipoprotein

any of the macromolecular complexes that are the form in which lipids are transported in the blood. They consist of a core of hydrophobic lipids covered by a layer of phospholipids and apoproteins, which make the complex water-soluble. There are four main classes of lipoproteins: chylomicrons, in which lipids are transported after a meal from the intestine to tissues, where they are stored or used; very low density lipoproteins (VLDL); low density lipoproteins (LDL); and high density lipoproteins (HDL). VLDL and HDL are produced by both the liver and the intestine; LDL is produced by the metabolism of VLDL.

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α-lipoprotein

high density lipoproteins which migrate in the alpha position in paper chromatography. Inherited deficiency of these proteins is described in humans but there is no known animal model of the disease.

lipoprotein factor Xa inhibitor

a blood coagulation inhibitor present in the low density lipoprotein fraction of plasma.

high density lipoprotein (HDL)

a fraction of lipoproteins separable by ultracentrifugation.

intermediate density lipoprotein (IDL)

intermediate in density between LDL and VLDL; migrate in electrophoresis with β-globulins.

lipoprotein lipase

specific lipase hydrolyzing lipoproteins.

lipoprotein lipase deficiency

see hyperlipoproteinemia.

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lipoprotein(a)

Lp(a) Physiology A lipoprotein with a range of serum levels, a lipid content similar to LDL, which binds to the LDL receptor with lesser affinity than LDL; Lp(a)'s role in ASHD is controversial; it is ↑ in Pts at risk for CAD Ref range 0-30 mg/dL

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Patient discussion about lipoprotein.

Q. what are the sources for high density lipoprotein? I have heard that high density lipoprotein is good for heart. What differences does it make in heart’s health and what are the sources for high density lipoprotein?

A. Hi Liam, it is very important that we have high density lipoprotein (HDL) in our body. The fact is that the HDL is formed inside the body. They are known as good cholesterol as they are famous for their protection for heart against the heart diseases. It has been found that Vitamin B3 or Niacin consumption increases the count of HDL. It’s good to cut on the diet having more of saturated fats and oils, which increases the chances of heart attack.