lipoperoxide

lipoperoxide

Pathophysiology A peroxide–an O-O containing free radicals–which has peroxidized the carbon atoms close to the double bonds in an unsaturated fatty acid. See Peroxide.
References in periodicals archive ?
Activation of peroxisome proliferator-activated receptor alpha by dietary fish oil attenuates steatosis, but does not prevent experimental steatohepatitis because of hepatic lipoperoxide accumulation.
Effects of silybin on production of oxygen free radical, lipoperoxide and leukotrienes in brain following ischemia and reperfusion.
Using necrotic models of hepatic cells in animal experiments, Rosser and Gores (1995) demonstrated the relationship between advancing hepatic dysfunction and lipoperoxide reaction (Rosser and Gores 1995).
Along with its role in Pb-induced hepatotoxicity, oxidative stress was also noted to play a significant role in the regression phase of hepatic hyperplasia with the generation of lipoperoxide (LPO) and other oxidants and the induced expression of cytokine mediators, including TNF-[alpha].
Changes in the levels of lipoperoxide and antioxidant factors in human placenta during gestation.
However, mean reference values for lipoperoxide concentrations in plasma of healthy adults (0.
Vitamin C is the safest, most powerful and ubiquitous free radical scavenger (antioxidant) known to biology and it can very quickly remove free radicals such as superoxide, nitric oxide, hydroxyl, lipoperoxides and peroxynitrates from organs and tissues.
These actions suggest that PON1 could prevent the accumulation of lipoperoxides in LDL and has a protective role against cardiovascular diseases and atherosclerosis (Figure 1).
Candidate factors include erythrocyte 2,3-diphosphoglycerate levels, intra-erythrocyte pH, and total plasma amino acid levels (8); lipoperoxides and antagonistic antioxidants (12); glycolytic and deglycating enzymes (6, 7, 21); processes related to glucose transporter 1-mediated transport (11); and erythrocyte transmembrane glucose gradient (27).