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lipoic acid

   Also found in: Encyclopedia, Wikipedia, Hutchinson 0.03 sec.
lipoic acid /lipo·ic ac·id/ (lip-o´ik) a necessary cofactor for several enzyme complexes involved in the oxidative decarboxylation of keto acids, where it occurs in the form lipoamide. It is used as a dietary supplement for its antioxidant properties.
li·po·ic acid (l-pk)
n.
An organic acid produced by cells of certain microorganisms and essential to oxidative decarboxylation of pyruvate to acetyl-CoA during metabolism. Also called factor II.

lipoic acid
a vitamin prosthetic group in enzymes involved in oxidative decarboxylation of keto acids such as 2-oxoglutarate and pyruvate. Called also a-lipoic acid, thioctic acid.

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Brian Day, National Jewish Medical and Research Center, to test the ability of lipoic acid, dihydrolipoic acid, and thioredoxin to reverse or prevent pulmonary injury caused by sulfur mustard
Tetracycline Antiseptics Acetic acid Alcohol Chlorhexidine Cresylate Gentian violet Vehicles Benzalkonium chloride Polyethylene glycol Propylene glycol Salicylates Nonsteroidal anti-inflammatory drugs Quinine Chemotherapeutic drugs Carboplatinum Cisplatinum Vinblastine Vincristine Loop diuretics Ethacrynic acid Furosemide Table 2 Agents that protect against ototoxicity Alpha lipoic acid Antioxidants Calcium Fosfomycin Glutathione Iron chelators
The other is scrutinizing natural antioxidants, such as vitamin E and alpha lipoic acid, in lab animals with EAE, an MS-like disease.
 
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