lipoic acid


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.
Related to lipoic acid: Alpha lipoic acid

li·po·ic ac·id

(li-pō'ik as'id),
A bacterial growth factor present in yeast and liver extracts; may be useful in the treatment of mushroom poisoning. Functions as the amide (lipoamide) cofactor in the disulfide (-S-S-) form in the transfer of "active aldehyde" (acetyl), the two-carbon fragment resulting from decarboxylation of pyruvate from α-hydroxyethylthiamin pyrophosphate to acetyl-CoA, itself being reduced to the dithiol form (that is, dihydrolipoic acid) in the process. Lipoic acid is also an essential component of other α-keto acid dehydrogenase complexes.

lipoic acid

/lipo·ic ac·id/ (lip-o´ik) a necessary cofactor for several enzyme complexes involved in the oxidative decarboxylation of keto acids, where it occurs in the form lipoamide. It is used as a dietary supplement for its antioxidant properties.

lipoic acid

(lĭ-pō′ĭk)
n.
An organic acid, C8H14S2O2, that is essential for decarboxylation of pyruvate to acetyl coenzyme A during aerobic metabolism. It is also used as a dietary supplement for its antioxidant properties.

lipoic acid

[lipō′ik]
a bacterial growth factor found in liver and yeast.

lipoic acid

a vitamin prosthetic group in enzymes involved in oxidative decarboxylation of keto acids such as 2-oxoglutarate and pyruvate. Called also α-lipoic acid, thioctic acid.
References in periodicals archive ?
Continuous infusion of lipoic acid rapidly reduces plasma beta-hydroxybutyrate with elevation of non esterified fatty acids in broiler chickens.
Lipoic acid regenerates glutathione and vitamins C and E.
They found that lipoic acid helped remediate some of the liver dysfunctions that are often common in old age, and significantly improved the function of their circadian rhythms.
In this report, you will discover how supplemental lipoic acid protects vital cellular energy while shielding against and possibly reversing the damaging effects of disorders that include diabetes, obesity, cardiovascular disease, neurodegeneration, and cancer.
Oral lipoic acid was generally well tolerated (the most common side effects were nausea and bad smelling urine), and it decreased key inflammatory molecules.
Now, Alpha Lipoic Acid will always be in our cupboard whether hubby is working or not.
Hagen showed that old, sluggish rats became as physically and mentally active as rats half their age within a few weeks of being fed ALCAR and lipoic acid.
3 Alpha lipoic acid and its reduced metabolic product dihydrolipoic acid (DHLA) both inhibited formation of beta-amyloid fibrils from beta-amyloid protein in vitro.
The researchers found that supplements of lipoic acid appeared to affect triglyceride levels through two pathways.
These results show that the antioxidant combination of Polygonum cuspidatum, ascorbic acid, bioflavonoids and lipoic acid enhanced the ability of the red blood cells to withstand oxidation for a significantly longer time than was possible with resveratrol or ascorbic acid alone.
Dermavite (below) is a combination of nutrients, including antioxidant alpha lipoic acid, pine bark extract, a marine protein complex, silicon and zinc.
The other is scrutinizing natural antioxidants, such as vitamin E and alpha lipoic acid, in lab animals with EAE, an MS-like disease.