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lipofuscinosis |
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lipofuscinosis /lipo·fus·cin·o·sis/ (-fu″sin-o´sis) any disorder due to abnormal storage of lipofuscins. neuronal ceroid-lipofuscinosis any of several genetic lipidoses characterized by progressive neurodegeneration, loss of vision, and a fatal course; included are Janský-Bielschowsky disease, Vogt-Spielmeyer disease, and Kufs' disease.
lipofuscinosis any disorder due to abnormal storage of lipofuscins. ceroid lipofuscinosis an inherited disease in sheep, cattle, dogs and cats, characterized by blindness, mental dullness and abnormal behavior. There is atrophy of the brain with extensive accumulation of lipopigments ('ceroid bodies') in nervous tissue and later viscera as well. The comparable, though possibly not identical, disease in humans is also called Batten disease. hepatic lipofuscinosis a deposit of lipofuscin in partly oxidized form in the livers of sheep, which gives them a deep black color and makes them unsaleable. The condition is common in areas where the mulga tree (Acacia aneura) grows and the leaves are fed to sheep as fodder. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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he crafted and filed a successful IND for human neural stem cell transplantation in neuronal ceroid lipofuscinosis. NASDAQ: STEM) which is designed to evaluate the safety and preliminary efficacy of HuCNS-SC[TM] as a treatment for infantile and late infantile neuronal ceroid lipofuscinosis (NCL). This transplant is the first of six that are planned as part of the Company's Phase I clinical trial designed to evaluate the safety and preliminary efficacy of HuCNS-SC as a treatment for infantile and late infantile neuronal ceroid lipofuscinosis (NCL). |
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