lipid-lowering therapy

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lipid-lowering therapy

drugs, dietary and lifestyle regimes directed toward restoring blood lipids to normal levels

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Currently, WOSCOPS and AFCAPS/TexCAPS are the only major primary prevention trials of lipid-lowering therapy in elderly populations.

Management of hyperlipidemia in the elderly population: an evidence-based approach

Data Source: A meta-analysis involving 44,255 patients in eight clinical trials of lipid-lowering therapy.

Benefits of lipid-lowering agents persist after trials end

All of these results were adjusted only for age and sex; however, similar results were seen when we additionally adjusted for lipid-lowering therapy (data not shown).

Nonfasting lipids, lipoproteins, and apolipoproteins in individuals with and without diabetes: 58 434 individuals from the Copenhagen General Population Study

There is recent clinical and experimental evidence that lipid-lowering therapy, such as statins, can restore normal heart rhythms, thus helping to prevent sudden death," Dr.

How too much cholesterol puts life at risk

In contrast, the AF patients on lipid-lowering therapy demonstrated significant improvement over baseline in speed of information processing, memory, and executive function as assessed by switching tests.

Lipid lowering reverses cognitive decline in some atrial fibrillation

Although lipid-lowering therapies, including statins, may lower Lp-PLA2 levels, pharmacologic interventions are now being studied to find ways of best inhibiting the Lp-PLA2 enzyme and potentially providing incremental benefit to intensive lipid-lowering therapy.

Inflammatory-Enzyme Shown to Predict Risk of Cardiovascular Events After Acute Coronary Syndromes

Low-density lipoprotein cholesterol (LDL-C) is the primary target of lipid-lowering therapy, as the link between LDL-C and CAD is well established.

Clinical utility of bile acid sequestrants in the treatment of dyslipidemia: a scientific review

In addition, only half of the women who met the criteria of the National Cholesterol Program II guidelines for lipid-lowering therapy were taking statins or other lipid-lowering treatments at enrollment (Ann.

CHD prevention underused in older, high-risk women. (Statins, [beta]-Blockers)

The sub analysis showed a 47 per cent reduction in LDL-C levels among stable coronary artery disease (CAD) patients who remained event-free following aggressive lipid-lowering therapy with LIPITOR(R) (atorvastatin calcium).

TRIAL SHOWS LIPID-LOWERING HAS CARDIOVASCULAR BENEFIT

Senior Research Manager at Express Scripts, showed that physicians' use of Corus CAD was associated with increased medication adherence among patients prescribed lipid-lowering therapy.

CardioDx Announces New Data Supporting the Clinical Utility and Validity of Corus CAD at the American Heart Association Scientific Sessions 2012

Individuals are then stratified into low risk (< 10% risk over 10 years), intermediate risk (10% to 20% risk over 10 years), or high -risk (>20% risk over 10 years) based on their score (1), and this risk score then guides a clinician's decision to institute antiplatelet or lipid-lowering therapy or advise intensive lifestyle modification.

Thirty-year multivariate risk assessment is a stronger predictor of cardiovascular disease than the 10-year model

Although there is room for improvement, particularly in very high-risk patients, these results indicate that lipid-lowering therapy is being applied much more successfully than it was a decade ago," said David D.