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linkage analysis |
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linkage analysis Genetics A gene-hunting technique that traces patterns of heredity in large, high-risk families, in an attempt to locate a disease-causing gene mutation by identifying traits co-inherited with it; the formal study of the
association between the inheritance of a condition in a family and a particular chromosomal locus; LA is based on certain ground rules of genetics. See Lod score. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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We have also performed sib-pair linkage analysis using data from dizygotic (DZ) twin pairs to identify quantitative trait loci (QTLs) affecting blood lead concentration. The process is called linkage analysis, and corporations Mr. First, it is important to show that the criteria measure has external validity and is related to measures that might be used in a more fully developed linkage analysis. |
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