linkage

linkage /link·age/ (lingk´ij)

1. the connection between different atoms in a chemical compound, or the symbol representing it in structural formulas; see also bond.

2. in genetics, the association of genes having loci on the same chromosome, which results in the tendency of a group of such nonallelic genes to be associated in inheritance.

3. in psychology, the connection between a stimulus and its response.

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link·age (lngkj)

n.

An association between two or more genes such that the traits they control tend to be inherited together.

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linkage

[ling′kij]

Etymology: Gk, linke, connection

1 (in genetics) the location of two or more genes on the same chromosome so that they do not segregate independently during meiosis but tend to be transmitted together as a unit. The closer the loci of the genes, the more likely they are to be inherited as a group and associated with a specific trait, whereas the farther apart they are, the greater the chance that they will be separated by crossing over and carried on homologous chromosomes. The concept of linkage, which opposes the independent assortment theory of mendelian genetics, led to the foundation of the modern chromosome theory of genetics. See also synteny.

2 (in psychology) the association between a stimulus and the response it elicits.

3 (in chemistry) the bond between two atoms or radicals in a chemical compound or the lines used to designate valency connections between the atoms in structural formulas.

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linkage,

n 1. in genetics, the location of two genes on the same chromosome such that they are typically transmitted as a cohesive unit during meiosis.
2. in psychology, the relationship between a response and its stimulus.

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linkage (ling´kj),

n the connection between two or more objects. In computer programming, coding that connects two separately coded routines.

linkage, cross,

n See polymerization, cross.

linkage, sex,

n the inheritance of certain characteristics that are determined by genes located in the sex chromosomes.

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linkage

1. the connection between different atoms in a chemical compound, or the symbol representing it in structural formulae. See also bond.

2. in genetics, the association of genes having located on the same chromosome, which results in the tendency of a group of such nonallelic genes to be associated in inheritance (linkage disequilibrium). Called also syntenic group.

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disequilibrium linkage

the inheritance of two alleles together at a higher than expected frequency.

linkage map

see genetic map.