linitis plastica


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linitis

 [lĭ-ni´tis]
inflammation of gastric cellular tissue.
linitis plas´tica diffuse fibrous proliferation of the submucous connective tissue of the stomach, resulting in thickening and fibrosis so that the organ is constricted, inelastic, and rigid (like a leather bottle). Called also leather bottle stomach.

li·ni·tis plas·ti·ca

originally believed to be an inflammatory condition, but now recognized to be due to infiltrating scirrhous carcinoma causing extensive thickening of the wall of the stomach; often called leather-bottle stomach.

linitis plastica

a diffuse fibrosis and thickening of the wall of the stomach, resulting in a rigid, inelastic organ. The layer of connective tissue of the stomach becomes fibrotic and thick, and the stomach wall becomes shrunken and rigid. Causes of this condition include infiltrating undifferentiated carcinoma, syphilis, and Crohn's disease involving the stomach. Also called leather-bottle stomach.

linitis plastica

A descriptive term of waning popularity that refers to the appearance of certain hollow organs in which there is a rigidly thickened wall, which classically occurs in signet ring cell adenocarcinoma of the stomach.
 
Imaging
Upper GI series demonstrates neither ulcer nor mass, but a fixed, non-distensible stomach, absent folds and narrowed lumen, likened to the Spanish leather wineskin, la bota. Linitis plastica may rarely occur in other hollow epithelial cell-lined organs (e.g., colon or bladder).

li·ni·tis plas·ti·ca

(li-nī'tis plas'ti-kă)
Infiltrating scirrhous carcinoma, causing extensive thickening of the wall of the stomach; often called leather-bottle stomach.

Brinton,

William, English physician, 1823-1867.
Brinton disease - infiltrating scirrhous carcinoma causing extensive thickening of stomach wall. Synonym(s): leather-bottle stomach; linitis plastica

linitis

inflammation of gastric cellular tissue.

linitis plastica
inelastic thickening and fibrosis of the gastric submucosa; called also leather bottle lesion.
References in periodicals archive ?
No previous reports on the lipoid cell variant of UC have reported a linitis plastica tumour morphology.
SRCs in the GI tract most often produce a primary linitis plastica tumour morphology and are frequently documented in primary RLP,[sup.
Secondary linitis plastica of the rectum: EUS features and tissue diagnosis (with video).
Some specific radiological findings and consideration of linitis plastica of the gastrointestinal tract.
Linitis plastica caused by metastatic lobular carcinoma of the breast.
Cormier WJ, Gaffey TA, Welch JM, et al: Linitis plastica caused by metastatic lobular carcinoma of the breast.
Pathologic Diagnosis: Linitis Plastica Secondary to Metastatic Breast Carcinoma
Linitis plastica may be primary, caused by diffuse gastric carcinoma, or secondary to metastatic disease.
Pathologic and radiographic patterns of gastric metastases include microscopic or palpable induration only, without any radiographic abnormality; solitary or multiple nodular masses that present as filling defects; and diffuse infiltration of the gastric wall that simulates linitis plastica.
Diffusely infiltrating tumors can cause gastric rigidity, resulting in linitis plastica shown by limited distension after administration of oral contrast.
A linitis plastica appearance, with luminal narrowing and rigidity, and thickened folds suggest diffuse gastric involvement (16, 17).