linear dose-response

linear dose-response

A consistent increase in biological response as increased quantities of a test substance are administered.

linear dose-response

Therapeutics A consistent ↑ in biologic response as ↑ quantities of a test substance are administered
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This adherence to linear dose-response ideology produces confusion in the face of conflicting results.
The linear dose-response relationship showed the risk of stroke decreased by 32% (0.
A key question is whether the recent epidemiological literature supports estimates of cancer risk predicted from linear dose-response models.
Cadmium, diesel, lead, manganese, mercury, methylene chloride, and nickel showed roughly linear dose-response relationships between concentration and odds ratio of ASD.
Like most other scientists studying BPA,' we do not see a straightforward linear dose-response relationship," she said.
Although the observed relative risk of stroke was modest, the findings suggest that "if the association between stroke and pollution is causal and a linear dose-response occurs, a 2-mi-crogram/m3 reduction in mean PM2 5 levels (approximately 20%) during this time period might have averted approximately 6,100 of the 184,000 stroke hospitalizations observed in the U.
The linear dose-response relationship of the LPA variants with both the Lp(a) lipoprotein level and the risk of coronary disease provided compelling support for a causal role of an elevated plasma level of Lp(a) lipoprotein and the risk of coronary disease," the researchers said.
The meta-analysis of data from 2,274 women with breast cancer and 2,268 controls without breast cancer indicated a linear dose-response gradient between serum 25(OH)D levels and the risk of breast cancer.
Top line Phase IIb US trial results were announced in January, showing that Dyloject(TM) met its primary endpoint of linear dose-response for pain relief over six hours.
Given our opinion, we further believe that the actual risk from low-level exposure is likely to be much less than EPA's linear dose-response model indicates.
The steep and linear dose-response relationship for both the virilizing and anabolic actions of testosterone, ranging from the concentrations in childhood and in females (<2 nmol/L) to the normal adult male physiological range (10-35 nmol/L), is indisputable (Fig.
Reversal of Heparin by Novel Synthetic Antagonist PMX-60056 Exhibits a Linear Dose-Response Relationship

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