linear IgA bullous disease

linear IgA bullous disease,

a condition characterized by linear deposits of immunoglobulin A binding to the area of the lamina lucida. Tense bullae are frequent, and the vesicles are likely to occur on the face, thighs, feet, and flexures. The disease tends to affect women more than men, and half of the patients are under the age of 60. A chronic bullous dermatosis disease of childhood begins in the first 10 years of life with bullae on the trunk, perioral, and pelvic areas but undergoes total remission at adolescence.