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lincomycin

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.11 sec.
lincomycin /lin·co·my·cin/ (lin″ko-mi´sin) an antibiotic, primarily a gram-positive specific antibacterial, produced by a variant of Streptomyces lincolnensis; used as the hydrochloride salt.
lincomycin
(ling´kmī´sin),
n brand names: Lincocin, Lincorex;
drug class: antibacterial;
action: binds to 50S subunit of bacterial ribosomes; suppresses protein synthesis;
uses: infections caused by group A β-hemolytic streptococci, pneumococci, staphylococci (respiratory tract, skin, soft tissue, urinary tract infections; osteomyelitis; septicemia), and anaerobes. Lincomycin should be reserved for pencillin-allergic patients. Close clinical supervision is required because severe colitis has been associated with lincomycin therapy.

lincomycin
a lincosamide antibiotic produced by Streptomyces lincolnensis; used as the hydrochloride salt.

lincomycin-associated colitis
a disease of horses resembling colitis-X occurring in horses receiving therapy with lincomycin; an organism resembling Clostridium cadaveris has been suggested as a cause.

lincomycin
Lincocin® An older generation antibiotic produced from Streptomyces lincolnensis, which has been used for gram-positive cocci


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An ear swab culture yielded Staphylococcus aureus, which was sensitive to lincomycin and vancomycin.
The strain was sensitive to penicillin, ampicillin, gentamicin, rifampin, vancomycin, teicoplanin, tetracycline, sulfamethoxazole, trimethoprim, fusidic acid, ciprofloxacin, and norfloxacin and resistant to erythromycin, lincomycin, and nitrofurantoin.
Among the antibiotics used are ampicillin, bacitracin, erythromycin, lincomycin, virginiamycin, and tetracycline (Food and Drug Administration 2004), some of which are important in human clinical medicine.
 
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