limit of quantitation


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Related to limit of quantitation: sensitivity

limit of quantitation

Abbreviation: LOQ
The smallest amount of analyte that can be measured with stated and acceptable imprecision and inaccuracy e.g., the smallest number of viral particles detectable in a milliliter of blood. See: limit of detection; sensitivity
See also: limit
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References in periodicals archive ?
Method Precision/Accuracy/Range - Establish by spiking sample matrix with compound of interest at levels ranging from limit of quantitation to two times the specification limit.
The performance characteristics that should be validated will vary depending on the purpose of the procedure and may include accuracy (precision and bias), limit of detection, limit of quantitation, linearity, working range, and selectivity.
EP17-A--Protocols for Determination of Limits of Detection and Limits of Quantitation; Approved Guideline for determining or verifying the lower limit of detection or LoD and lower limit of quantitation or LoQ of a method.
Limit of quantitation must be determined for all quantitative methods.
More specifically, the plasma levels of intact KP106 prodrug were below the limit of quantitation at all time points, whereas intact Vyvanse[R] levels were detectable and similar to previous reports.
v) Limit of quantification: the limit of quantitation (LOQ) was determined using formula LOQ = 10(SD)/S, where SD is standard deviation of response and S is average of slope of the calibration curve.