ligand-binding site

lig·and-bind·ing site

the site on a protein's surface that binds a ligand; equivalent to the active site if the ligand is the substrate of an enzyme.

li·gand-bind·ing site

(lī'gand-bīnd'ing sīt)
The site on the surface of a protein that binds a ligand; equivalent to the active site if the ligand is the substrate of an enzyme.
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References in periodicals archive ?
Ligand-gated ion channels typically consist of an extracellular domain that includes the ligand-binding site and a transmembrane domain that includes the ion pore.
GSTs consist of a specific-glutathione (GSH)-binding site (G-site) next to a non-specific electrophilic ligand-binding site (H-site).
Interactions between these odorants and receptors in the ligand-binding site will be modelled by studying complexes formed between odorants and mimics of amino acid residues.
and can be inhibited by phosphocholine, indicating that the single promiscuous ligand-binding site on the B face can accommodate diverse structural groups.
METHODS: We performed computational modeling to determine interaction energies between the ligand and the AR ligand-binding site, and measured in vitro competitive binding assays for AR by polarization fluorometry analysis.
Lipocalins have a conserved folding pattern consisting of antiparallel [beta]-strands that form a [beta]-barrel with a distinct ligand-binding site.
This type of response would be expected if hER possesses multiple ligand-binding sites displaying cooperative behavior as has been reported (14,16).