leukotriene receptor antagonists

leukotriene receptor antagonists

drugs that block the binding of leukotrienes to cysteinyl leukotriene T1 receptors, thus inactivating the action of leukotrienes.
See also: antileukotriene.

leukotriene receptor antagonists

Drugs that prevent the action of LEUKOTRIENES by blocking their receptors on cell membranes, such as those of smooth muscle. These drugs have a useful dual effect in relaxing the smooth muscle of the air passages (bronchi) and in combatting inflammation in the bronchial linings-both features of ASTHMA. They have also been found useful in hay fever. Examples are montelukast (Singulair) and zafirlukast (Accolate).
References in periodicals archive ?
In contrast, sinonasal imaging should not be routine when patients first present with symptoms consistent with allergic rhinitis, and oral leukotriene receptor antagonists are not recommended as first-line therapy, said Dr.
The active ingredient in the drug, Montelukast is in a class of medications called leukotriene receptor antagonists.
Leukotriene receptor antagonists and 5-lipoxygenase inhibitors are used to treat asthma patients, about 15% of whom are sensitive to cyclooxygenase inhibitors.
The tablets, called leukotriene receptor antagonists, are currently recommended as third or fourth steps in asthma treatment because of the belief that they are less effective.
They found that tablets called leukotriene receptor antagonists (LTRAs) managed the disease equally successfully as steroid inhalers and other "preventer" inhalers when used in addition to steroid inhalers.
They found that tablets called leukotriene receptor antagonists (LTRAs) managed the disease equally successfully as steroid inhalers for patients with mild asthma and in a parallel sample of patients with moderate asthma, LTRAs managed the disease equally successfully as other "preventer" inhalers when used in addition to steroid inhalers.
However, there have been many studies examining the effects of leukotriene receptor antagonists on allergic rhinitis in children.
Of the leukotriene receptor antagonists, the most data are available on montelukast (Singulair).
These patients seem to respond favorably to inhaled corticosteroids and leukotriene receptor antagonists.
6,7) Leukotriene receptor antagonists are no more effective than antihistamines and are less effective than intranasal corticosteroids in the treatment of allergic rhinitis.
Asthma medications known as leukotriene receptor antagonists are particularly useful in treating cough due to asthma, he adds.
Eosinophilic esophagitis can be treated with inhaled aerosolized steroids, systemic steroids, and leukotriene receptor antagonists, as well as by following an elimination/elemental diet.