leukotoxin

leukotoxin

 [loo´ko-tok″sin]
a toxin that destroys leukocytes.

leu·ko·cy·to·tox·in

(lū'kō-sī'tō-tok'sin),
Any substance that causes degeneration and necrosis of leukocytes, including leukolysin and leukocidin.
Synonym(s): leukotoxin
[leukocyte + G. toxikon, poison]

leukotoxin

/leu·ko·tox·in/ (loo´ko-tok″sin) a cytoxin destructive to leukocytes.

leukotoxin

[lo̅o̅′kətok′sin]
Etymology: Gk, leukos + toxikon, poison
a substance that can inactivate or destroy leukocytes. leukotoxic, adj.

leu·ko·cy·to·tox·in

(lū'kō-sī'tō-tok'sin)
Any substance that causes degeneration and necrosis of leukocytes, including leukolysin and leukocidin.
Synonym(s): leukotoxin.
[leukocyte + G. toxikon, poison]

leukotoxin

a toxin that destroys leukocytes.
References in periodicals archive ?
e coagulase, clumping factors, haemolysin and leukotoxin, pyogenic toxins comprising staphylococcal enterotoxins, toxic shock syndrome toxin 1, and S.
Leucotoxic activities of Staphylococcus aureus strains isolated from cows, ewes, and goats with mastitis: importance of LukM/LukF'-PV Leukotoxin.
32] The pathogenicity of the microorganism is also underlined by its well-characterized virulence factors, such as leukotoxin and cytolethal distending toxin, which are suggested to play important roles in altering host inflammatory responses as well as in contributing to periodontal disease progression.
Additional candidates have been highlighted in the literature, including the leukotoxin LukED which targets the human CCR5 receptor (Alonzo, 2013).
actinomycetemcomitans Leukotoxin Inhibition of PMN function.
aureus, including a leukotoxin comparable to the Panton-Valentine leukocidase as sociated with community-acquired S.
Maraviroc completely blocked the toxic effects of this leukotoxin at doses similar to those used to inhibit HIV infection," Dr.
Prevalence of systemic immunoreactivity to Aggregatibacter actinomycetemcomitans leukotoxin in relation to the incidence of myocardial infarction.
IL-1beta secretion induced by Aggregatibacter (Actinobacillus) actinomycetemcomitansis mainly caused by the leukotoxin.
Rabie G, Lally ET, Shenker BJ, Immunosuppresive Properties of Actinobacillus actinomycetemcomitans Leukotoxin.
Prevalence of genes encoding for members of the staphylococcal leukotoxin family among clinical isolates of Staphylococcus aureus.
As one example, consider that Aggregatibacter (formally Actinobacillus) actinomycetemcomitans produces a leukotoxin that alters the cell membranes of neutrophils and monocytes and thereby alters chemotactic and phagocytic responses.