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leukoerythroblastic reaction |
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leukoerythroblastic pertaining to or emanating from the production of erythrocytes. leukoerythroblastic reaction a bone marrow response in which nucleated red blood cells and immature leukocytes are released. Seen in all species, most commonly in dogs and cats. leukoerythroblastic reaction An ↑ in the peripheral blood of immature RBCs, ie normoblasts, and immature granulocytes, metamyelocytes and bands, which may be associated with metastatic cancer, hematopoietic malignancy, hemolytic anemia,
Gaucher's disease, polytrauma, BM infiltration by various processes, including infection–eg, fungal, viral, TB, sarcoidosis, histiocytosis, hypoxia;1⁄3 of Pts with LER have no known underlying disease. Cf
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The leukocyte alkaline phosphatase (LAP) score was within normal limits, and daily peripheral blood smears revealed no evidence of leukemic process or leukoerythroblastic reaction. |
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