leukoderma /leu·ko·der·ma/ (-der´mah) an acquired condition with localized loss of pigmentation of the skin.
leukoderma [loo″ko-der´mah]
leukoderma acquisi´tum centri´fugum halo nevus.
syphilitic leukoderma indistinct coarsely mottled hypopigmentation, usually on the sides of the neck, in late secondary syphilis.
leukoderma ac·qui·si·tum cen·trif·u·gum ( k w -s  t m s n-trfy-gm)n. See halo nevus. |
Halo Nevus
A pigmented melanocytic nevus surrounded by a peripheral zone of depigmentation—absence of melanocytes with a lymphohistiocytic infiltrate, measuring ± 5 mm in diameter surrounding a common nevus, affecting adolescents on the back; when inflamed, it is termed inflammatory halo nevus
DiffDx Congenital nevus, blue nevus, Spitz nevus, neurofibroma, primary and metastatic melanoma
Light microscopy The nevus is heavily infiltrated by lymphocytes and plasma cells which are thought to represent a host immune response, evoking a differential diagnosis of melanoma, lymphoma and dermatitis
DiffDx Congenital nevus, blue nevus, Spitz nevus, neurofibroma, primary and metastatic melanoma
Light microscopy The nevus is heavily infiltrated by lymphocytes and plasma cells which are thought to represent a host immune response, evoking a differential diagnosis of melanoma, lymphoma and dermatitis
leukoderma [loo″ko-der´mah]
an acquired condition with localized loss of pigmentation of the skin.
leukoderma acquisi´tum centri´fugum a pigmented nevus surrounded by a ring of depigmentation; see also halo nevus.
syphilitic leukoderma indistinct, coarsely mottled hypopigmentation, usually on the sides of the neck, in late secondary syphilis.
Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content.
| ?Page tools | ||
|---|---|---|
|