Assessing the potential leukemogenic
effects of 50 Hz magnetic fields and their harmonics using an animal leukemia model.
17) Long term safety of the drug, in particular of its Leukemogenic
potential is still questionable.
One naturally wonders whether the acute leukemic states that have occurred in some cases are due to the potentially leukemogenic
drug or are associated with the polycythemia.
Since APL is such a unique disorder and is sensitive to several less leukemogenic
medications, including ATRA and arsenic trioxide.
The P190, P210, and P230 forms of the BCR-ABL oncogene induce a simple chronic myelodic leukemia-like syndrome in mice but have different lymphoid leukemogenic
potential may need to be considered as part of the risks-and-benefits deliberation when recommending treatment for localized prostate cancer," he said.
For example, if there is a desire to determine whether benzene has been leukemogenic
In addition, the region of MLL that breaks and joins to other genes in leukemogenic
translocations is remarkably conserved at just over 8 kilobases (kb) in a central region of the gene.
Select the function that is NOT associated with leukemogenic
mechanisms in CML.
The Phase 2 study will be conducted at multiple centers in North America and is expected to enroll up to 60 patients with secondary AML (patients with antecedent myelodysplastic syndrome or prior exposure to leukemogenic
61] However, scientific documentation of, and substantial agreement on, benzene's leukemogenic
properties did not come for another sixty years, when the World Health Organization's International Agency for Research on Cancer ("IARC") addressed it.