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leukemogenesis |
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leukemogenesis [lo̅o̅kē′mōjen′əsis] the onset, development, or progression of leukemia. leukemogenesis the process of generation of myeloid cell lines in bone marrow and extramedullary sites; a critical feature in myeloproliferative disease; i.e. the induction or development of leukemia. leukemogenesis A process in which successive transformational events enhance the ability of hematopoietic progenitor cells to proliferate, differentiate, and survive. See Autonomous proliferation. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Vanderbilt University, Nashville, TN, "The role of proapoptotic BID in mediating apoptosis and the DNA damage response in myeloid homeostasis and leukemogenesis. Childhood leukemogenesis is likely a multistep process. The genotoxic metabolites are also thought to play an important role in benzene myelotoxicity and leukemogenesis. |
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