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leukemogenesis

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leu·ke·mo·gen·e·sis (l-km-jn-ss)
n.
Induction, development, and progression of a leukemic disease.

leukemogenesis
[lo̅o̅kē′mōjen′əsis]
the onset, development, or progression of leukemia.

leukemogenesis
the process of generation of myeloid cell lines in bone marrow and extramedullary sites; a critical feature in myeloproliferative disease; i.e. the induction or development of leukemia.

leukemogenesis
A process in which successive transformational events enhance the ability of hematopoietic progenitor cells to proliferate, differentiate, and survive. See Autonomous proliferation.


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Vanderbilt University, Nashville, TN, "The role of proapoptotic BID in mediating apoptosis and the DNA damage response in myeloid homeostasis and leukemogenesis.
The genotoxic metabolites are also thought to play an important role in benzene myelotoxicity and leukemogenesis.
 
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