leukapheresis

leukapheresis /leu·ka·phe·re·sis/ (loo″kah-fĕ-re´sis) the selective separation and removal of leukocytes from withdrawn blood, the remainder of the blood then being retransfused into the donor.

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leu·ka·phe·re·sis (lk-f-rss)

n.

The removal of a quantity of white blood cells from the blood of a donor with the remaining portions of the blood retransfused into the donor.

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leukapheresis

[lo̅o̅′kəfərē′sis]

Etymology: Gk, leukos + aphairesis, removal

a process by which blood is withdrawn from a vein, white blood cells are selectively removed, and the remaining blood is reinfused in the donor. It is a treatment or supportive care measure in patients with leukocytosis R/T leukemia. The white blood cells may be used for treating patients with blood deficiencies or for research. Compare plasmapheresis, plateletpheresis. See also apheresis.

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leukapheresis [loo″kah-fĕ-re´sis]

the selective removal of leukocytes from withdrawn blood, which is then retransfused into the donor.

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leukapheresis

the selective removal of leukocytes from withdrawn blood, which are then retransfused into the donor. See also pheresis.

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leukapheresis

Therapeutics The removal of blood to collect specific blood cells; plasma is returned to the body. See Apheresis Transfusion medicine The separation of leukocytes from whole blood with/without platelets with continuous or intermittent return of the RBCs and platelet- and leukocyte-poor plasma to a donor. See Cytapheresis, Hemapheresis, Plateletpheresis

Leukapheresis types  

'Harvesting' leukapheresis WBCs are donated from healthy subjects to immunocompromised and leukopenic Pts, which may be effective in short-term therapy of acute infections; long-term, Pts become either immunized against the donor antigens or infected with pathogens; 10¹⁰ granulocytes are needed for adequate 'coverage' against infections; to maximize the harvest, the donor receives corticosteroids

Reduction leukapheresis WBCs that compromise normal circulation are removed to temporarily relieve Sx of hyperleukemia–> 100 x 109/L; in a typical procedure, ± 6 liters of whole blood are processed to remove 5-10 x 109 WBCs

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