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leucovorin

   Also found in: Acronyms, Encyclopedia, Wikipedia 0.04 sec.
leucovorin /leu·co·vo·rin/ (-vor´in) folinic acid; the calcium salt is used as an antidote for folic acid antagonists, e.g., methotrexate, and in the treatment of megaloblastic anemias due to folic acid deficiency and colorectal carcinoma.
leu·co·vo·rin (lk-vôrn, l-kvr-n)
n.

leucovorin.
leucovorin


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The Food and Drug Administration (FDA) today announced the approval of Eloxatin (oxaliplatin) injection for use in combination with infusional 5-fluorouracil (5-FU) and leucovorin for the treatment of patients with colorectal cancer whose disease has recurred or become worse following initial therapy with a combination of irinotecan with bolus 5-FU and leucovorin.
Although drugs against the infection are already available, researchers have considered trimetrexate a less toxic or more effective alternative if used in conjunction with leucovorin.
AVASTIN([R]) and Leucovorin are also being administered in treating colorectal patients.
 
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