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leucovorin |
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leucovorin /leu·co·vo·rin/ (-vor´in) folinic acid; the calcium salt is used as an antidote for folic acid antagonists, e.g., methotrexate, and in the treatment of megaloblastic anemias due to folic acid deficiency and colorectal carcinoma.
leucovorin. See folinic acid. leucovorin [loo″ko-vor´in] leucovorin calcium the calcium salt of folinic acid, used as an antidote for folic acid antagonists, e.g., methotrexate, when there is need to reverse the toxic effects of the latter, in the treatment of megaloblastic anemias due to folic acid deficiency, and as an adjunct in the palliative treatment of colorectal carcinoma; administered orally, intramuscularly, or intravenously.
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