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lethal midline granuloma |
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Because malignant lymphomas are associated with surface crusting, widespread necrosis, and inflammation, they were once considered to be inflammatory lesions, known as lethal midline granulomas or nonhealing granulomas. Classification of nasal granulomas Infectious Mycobacterial: Tuberculosis (human, bovine, or avian); atypical tuberculo- sis; leprosy Bacterial: Rhinoscleroma Treponemal: Syphilis; yaws Fungal: Mucormycosis; aspergillosis; blastomycosis; histoplasmosis; coccidiomycosis; rhinosporidiosis Parasitic: Leishmaniasis Noninfectious Wegener's granulomatosis Sarcoidosis Inclusion granuloma (silicosis; berylliosis) Foreign-body retention Malignant Lethal midline granuloma Nonspecific It is now recognized that the vast majority of cases of lethal midline granuloma represent nasal T-cell lymphomas. |
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