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lethal factor

   Also found in: Acronyms 0.01 sec.
lethal factor
n.
A gene mutation or chromosomal structural change that when expressed causes death before sexual maturity.


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The microbe's toxin is made up of three key parts: edema factor (EF), lethal factor (LF), and protective antigen (PA).
In the German laboratory, the anti-PA enzyme-linked immunosorbent assay result was negative, but specific antibodies against lethal factor of B.
One of these is lethal toxin (made of lethal factor and protective antigen), which has been postulated to cause overproduction of inflammatory cytokines IL-1, IL-6 and TNF-alpha(Tumor Necrosis Factor).
 
 
 
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