lethal equivalent

le·thal e·quiv·a·lent

1. a combination of selective effects that on average have the same impact on the composition of the gene pool as one death; for example, two carriers at 50% risk of dying would be the lethal equivalent of one carrier at 100% risk;
2. in the population genetics of recessive traits, lethal equivalent is expressed as twice the sum of the expected number of deaths ascribable to the genetic load.
3. expression used of the genetic load of recessive genes in heterozygous state that if in homozygous state would cause death or carry a risk of death. The expected number of deaths from all such genes is expressed in lethal equivalent.

lethal equivalent

Etymology: L, letum, death, aequus, equal, valere, to be strong
a recessive allele carried in the heterozygous state that would be lethal in the homozygous state, or any combination of alleles, each with slightly deleterious effects, that are equivalent to such an allele. It is estimated that a person carries an average of three to eight lethal equivalents. See also lethal allele.

le·thal equiv·a·lent

(lēthăl ē-kwivă-lĕnt)
1. Combination of selective effects that on average have the same impact on the composition of the gene pool as one death.
2. In the population genetics of recessive traits, lethal equivalent is expressed as twice the sum of the expected number of deaths ascribable to the genetic load.
3. Expression used of the genetic load of recessive genes in heterozygous state that if in homozygous state would cause death or carry a risk of death. The expected number of deaths from all such genes is expressed in lethal equivalent.