leptomeningeal


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lep·to·me·nin·ge·al

(lep'tō-mĕ-nin'jē-ăl),
Pertaining to the leptomeninges.

lep·to·me·nin·ge·al

(lep'tō-mĕ-nin'jē-ăl)
Pertaining to the leptomeninges.

leptomeninges

(lep?to-men-in'jes) leptomeninx [? + meninx, membrane]
The pia mater and arachnoid as distinct from the dura mater.
Synonym: pia-arachnoidleptomeningeal, adjective

leptomeningeal

Pertaining to the two soft inner layers of membrane that surround the brain, the PIA MATER and the ARACHNOID MATER, but not the DURA MATER.
References in periodicals archive ?
Elevated ICP has been implicated in the development of leptomeningeal cysts.
Induction of multiple brain tumors (gliomata and leptomeningeal sarcomata) in dogs by Rous sarcoma virus.
Radiotherapy is the most common treatment for patients with multiple brain metastases or leptomeningeal involvement.
Leptomeningeal enhancement and a parenchymal mass with enhancement were also seen.
Ossified retroperitoneal malignant Schwannoma with spinal leptomeningeal metastases.
All patients with a miliary distribution had leptomeningeal nodules, and 18% of these patients had deep parenchymal nodules in addition.
A negative CSF cytology does not preclude leptomeningeal spread.
Gadolinium-enhanced MRI can provide definitive evidence of leptomeningeal metastases, although its reported sensitivity is only 75%.
In cases of breast cancer, the diagnoses of parenchymal brain metastases and leptomeningeal carcinomatosis are often delayed (1).
The company is currently completing the filing of a New Drug Application for its lead product, DepoCyt, an anti-cancer therapeutic for the treatment of neoplastic meningitis (also known as leptomeningeal metastases) arising from sold tumors and is continuing Phase III clinical trials for leukemia and lymphoma indications.