Study of the seroconversion of the thermostable live attenuated lentogenic
strain (local isolate) ND vaccine in layer and backyard birds.
The cleavage site of the velogenic and/or mesogeneic strains of NDVs has amino acid sequence motif 112R/KRQR/KRF117 in the F protein, whereas the lentogenic
viruses have amino acid sequence of 112G/EK/RQG/ERL117 (Wei et al.
Effects of Vaccination with Lentogenic
Vaccine and Challenge with Virulent Newcastle Disease Virus on Egg Production in Commercial and SPF Chickens.
The different expression of immune-related cytokine genes in response to velogenic and lentogenic
Newcastle disease viruses infection in chicken peripheral blood.
It belong to the family paramyxoviridae based on pathogenicity, the virus can be differentiated in to lentogenic
mesogenic, velogenic strain.
This includes viscerotropic velogenic, neurotropic velogenic, mesogenic, lentogenic
, and asymptomatic enteric forms.
ND is mostly caused by velogenic strains of NDV rather than mesogenic or lentogenic
strains which about 80-100% and 25% mortality, respectively, from disease [3-5].
There are three important pathotypes of ND virus, Velogenic, Mesogenic and Lentogenic
based on the virulence in infected birds, NDV has been classified into three pathotypes: Lentogenic
, which causes mild or in-apparent respiratory disease, Mesogenic, which produces respiratory and nervous signs with moderate mortality and the velogenic, which causes severe gastrointestinal lesions and neurological disease resulting in death of infected birds (14).
(nonvirulent) strains that produce mild signs with negligible mortality.
The lyophilized samples contained La Sota--like strains classified as lentogenic
Comparative morphometric analysis of vaccine virulence of some lentogenic
strains of Newcastle disease virus in tracheas of SPF chickens Arq.